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Status |
Public on Aug 09, 2017 |
Title |
Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-based Subtypes |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We performed an integrated genomic analysis of NPC using a large clinical cohort of treatment-naïve tumor specimens which identified three gene expression-based subtypes differing in their pattern of immune and stromal gene expression.
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Overall design |
mRNA-sequencing to quantify genome-wide transcript levels in 113 fresh, treatment-naive undifferentiated nasopharyngeal carcinoma tumors.
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Contributor(s) |
MacIsaac KD, Yao Y |
Citation(s) |
28851814 |
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Submission date |
Aug 08, 2017 |
Last update date |
May 15, 2019 |
Contact name |
Kenzie MacIsaac |
E-mail(s) |
kenzie.macisaac@gmail.com
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Phone |
617-992-3217
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Organization name |
Merck Research Labs
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Department |
Genetics and Pharmacogenomics
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Street address |
33 Avenue Louis Pasteur
|
City |
Boston |
State/province |
MA |
ZIP/Postal code |
02115 |
Country |
USA |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (113)
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Relations |
BioProject |
PRJNA397538 |
SRA |
SRP115011 |