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| Status |
Public on Jan 01, 2019 |
| Title |
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Generation of preclinical models which recapitulate at best the extreme intra-tumoral heterogeneity (using two cell culture conditions) and inter-tumor heterogeneity between children diagnosed with high-grade gliomas.
|
| |
|
| Overall design |
Gene expression modulation was assess by high-throughput RNA sequencing between monolayer and neurosphere cell culture exposed to deprivation of oxygen described in tumor patient versus normal condition (normoxy).
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| |
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| Contributor(s) |
Blandin A, Durand A, Entz-Werle N |
| Citation(s) |
31779235, 34067180 |
| |
| Submission date |
Jul 24, 2017 |
| Last update date |
Jul 15, 2021 |
| Contact name |
Anne-Florence Blandin |
| E-mail(s) |
anneflorence.blandin@gmail.com
|
| Organization name |
University of Strasbourg
|
| Department |
Hautepierre hospital
|
| Lab |
EA3430
|
| Street address |
3 avenue molière
|
| City |
strasbourg |
| State/province |
bas-rhin |
| ZIP/Postal code |
67200 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA395554 |
| SRA |
SRP113456 |
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