|
| Status |
Public on Oct 25, 2017 |
| Title |
Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation [ChIP-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Disruption of Ski/Smad4 license Th17 differentiation. TGF-b-Ski-Smad4-RORgt-Th17 axis
|
| |
|
| Overall design |
Examination of Smad4 ChIP-seq in two different cells (WT vs.Smad4 KO) under IL6+TGFbR inhibitor condition
|
| |
|
| Contributor(s) |
Zhang S, Xu X, Wan Y |
| Citation(s) |
29072299 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 AI123193 |
Functional protein networks underlying T cell growth, proliferation and differentiation |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
Yisong Wan |
|
| |
| Submission date |
Jul 18, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Yisong Wan |
| Organization name |
University of North Carolina-Chapel Hill
|
| Department |
Lineberger Comprehensive Cancer Center
|
| Lab |
Marsico Hall Rm 5229J
|
| Street address |
125 Mason Farm Road
|
| City |
Chapel Hill |
| State/province |
NC |
| ZIP/Postal code |
27599 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA394907 |
| SRA |
SRP112757 |
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