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| Status |
Public on Nov 10, 2017 |
| Title |
Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos through inhibition of apoptosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We generated hESCs with inducible expression of anti-apoptotic gene BCL2 and BCL2L1, and found that the BCL2- and BCL2L1-overexpression could inhibit apoptosis of hESCs without affecting their pluripotent state.
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| |
|
| Overall design |
mRNA profiles of human embryonic stem cells with inducible expression of anti-apoptotic gene BCL2 and BCL2L1 were generated by RNA sequencing using Illumina HiSeq 4000
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| |
|
| Contributor(s) |
Li T, Feng G |
| Citation(s) |
29099092 |
| |
| Submission date |
Jul 06, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Qi Zhou |
| E-mail(s) |
zhouqi@ioz.ac.cn
|
| Organization name |
Institute of Zoology,CAS
|
| Lab |
Zhou
|
| Street address |
Datun Road, Chaoyang District
|
| City |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA393309 |
| SRA |
SRP111190 |
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