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| Status |
Public on Sep 11, 2017 |
| Title |
Analysis of transcriptome profiling in liver tissues of wild-type and SREBP1c knockout mice using RNA-seq |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Sterol regulatory element-binding protein 1c (SREBP1c) plays important roles in lipid metabolism and cell proliferation. To identify novel target genes of SREBP1c, particularly, in cell cycle regulation, we analyzed transcriptome profiling (RNA-seq) in liver tissue of wild-type and SREBP1c knockout mice. Liver transcriptome profiles of 12-week-old wild-type (C57BL/6) and SREBP1c KO mice were generated by mRNA-seq, in duplicate, using Illumina HiSeq4000 by MACROGEN, Inc (Korea).
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| |
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| Overall design |
Analysis of transcriptome profilings (RNA-seq) in liver tissue of wild-type and SREBP1c knockout mice
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| |
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| Contributor(s) |
Kim J, Lee J, Jeon Y, Jang H, Park J |
| Citation(s) |
28827316 |
| |
| Submission date |
Jul 05, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jae Bum Kim |
| Organization name |
Seoul National University
|
| Department |
Biology
|
| Lab |
Lab of Adipocytes and Metabolism Research
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| Street address |
105-333 Gwanak-ro 1
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| City |
Seoul |
| ZIP/Postal code |
08826 |
| Country |
South Korea |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA393188 |
| SRA |
SRP111134 |
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