|
| Status |
Public on Jan 31, 2018 |
| Title |
Defining the responses governing disease tolerance during Citrobacter rodentium infection of mice by deep RNA sequencing |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed deep RNA sequencing and systematically analyzed the global gene expression profiles of C. rodentium-infected colon tissues from both susceptible and resistant congenic mice strains to determine the common transcriptomic responses to infection and the Rspo2-mediated dysregulated pathway signatures associated with the loss of disease tolerance.
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| |
|
| Overall design |
C. rodentium infection in OuJ and O.B6 mice strains
|
| |
|
| Contributor(s) |
Gruenheid S, Kang E, Zhou G |
| Citation(s) |
29339782 |
| |
| Submission date |
Jun 27, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Samantha Gruenheid |
| E-mail(s) |
samantha.gruenheid@mcgill.ca
|
| Phone |
(514) 398-2138
|
| Organization name |
McGill University
|
| Department |
Microbiology and Immunology
|
| Street address |
3649 Promenade Sir-William-Osler, Room 365
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3G 0B1 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA392087 |
| SRA |
SRP110594 |
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