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| Status |
Public on Sep 06, 2018 |
| Title |
RNA-seq data of lungs from mouse infected with different H5N1 Avian Influenza Viruses |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Long non-coding RNAs (lncRNAs) play multiple key regulatory roles in various biological processes. However, their function in influenza A virus (IAV) pathogenicity remains largely unexplored.
Here, using next generation sequencing, we systemically compared the whole-transcriptome response of the mouse lung infected either with high-pathogenic (A/Chicken/Jiangsu/k0402/2010, CK10) or with nonpathogenic (A/Goose/Jiangsu/k0403/2010, GS10) H5N1 strains.
A total of 370 significantly differentially expressed (DE) lncRNAs from three replicates were identified associated with the high virulence of CK10, whereas the corresponding number for GS10 was 229.
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| Overall design |
Total three biological samples are analyzied, each of them had triplication.The three samples are CK10-infected mouse lung,the GS10-infected mouse lung and Mock PBS-infected mouse lung.
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| Contributor(s) |
Hu J, Hu Z |
| Citation(s) |
30052469 |
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| Submission date |
Jun 27, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jiao Hu |
| E-mail(s) |
hujiao@yzu.edu.cn
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| Organization name |
Yangzhou University
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| Street address |
48 Wenhui Road
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| City |
Yangzhou |
| ZIP/Postal code |
225009 |
| Country |
China |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA392033 |
| SRA |
SRP110570 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE100522_1_Processed_data-mRNA.txt.gz |
1.3 Mb |
(ftp)(http) |
TXT |
| GSE100522_2_Processed_data-lncRNA.txt.gz |
2.7 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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