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| Status |
Public on Aug 01, 2017 |
| Title |
Transcriptome of neonatal preBötzinger Complex neurons in Dbx1 reporter mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We sequenced the transcriptome of brainstem interneurons in the specialized respiratory rhythmogenic site dubbed preBötzinger Complex (preBötC) from newborn mice. To distinguish molecular characteristics of the core oscillator we compared preBötC neurons derived from Dbx1-expressing progenitors that are respiratory rhythmogenic to neighbouring non-Dbx1-derived neurons, which support other respiratory and non-respiratory functions.
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| Overall design |
RNA-seq gene expression profile for preBötC neurons in newborn mice
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| Contributor(s) |
Hayes* JA, Kottick* A, Picardo* MC, Halleran AD, Smith RD, Smith GD, Saha MS, Del Negro CA |
| Citation(s) |
28819234, 30789900 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL104127 |
Neurophysiology of Breathing Behavior in Mice |
COLLEGE OF WILLIAM AND MARY |
Christopher A Del Negro |
| R21 NS087257 |
Role of TRP Channels in Respiratory Rhythm and Breathing |
COLLEGE OF WILLIAM AND MARY |
Christopher A Del Negro |
| R15 HD077624 |
Plasticity and Regulation in Xenopus Anterior-Posterior Patterning |
COLLEGE OF WILLIAM AND MARY |
MARGARET S SAHA |
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| |
| Submission date |
Jun 22, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Maria Cristina Picardo |
| E-mail(s) |
mrdegu@wm.edu
|
| Organization name |
College of William and Mary
|
| Department |
Applied Science, ISC 3
|
| Lab |
Systems Neuroscience
|
| Street address |
540 Landrum Dr
|
| City |
Williamsburg |
| State/province |
VA |
| ZIP/Postal code |
23185 |
| Country |
USA |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA391436 |
| SRA |
SRP110146 |
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