|
| Status |
Public on Sep 28, 2017 |
| Title |
MYCL and EP400 are required for Max and MCPyV mediated gene activation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To determine if MYCL or EP400 knockdown would affect Max target genes in Merkel cell carcinoma cell line MKL-1, we performed RNA-seq analyses of MKL-1 cells inducibly expressing shMYCL and two different EP400 shRNA -2, -3 and compared to ChIP-seq data using BETA analyses.
|
| |
|
| Overall design |
MYCL or EP400 was inducibly reduced with shRNA in MKL-1 cells to analyze gene regulation.
|
| |
|
| Contributor(s) |
Cheng J |
| Citation(s) |
29028833 |
| |
| Submission date |
Jun 19, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jingwei Cheng |
| E-mail(s) |
jingweic@gmail.com
|
| Phone |
617-632-4797
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Lab |
James A. DeCaprio
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (15)
|
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| This SubSeries is part of SuperSeries: |
| GSE69878 |
MCPyV ST activates Max target genes by recruiting TRRAP/EP400 complex |
|
| Relations |
| BioProject |
PRJNA390939 |
| SRA |
SRP109645 |
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