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    SELP selectin P [ Homo sapiens (human) ]

    Gene ID: 6403, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    High expression of angiotensin-converting enzyme 2 receptor (ACE-2), transmembrane protease serine (TMPRSS), and P-selectin in platelets lead to thrombosis formation in COVID-19 patients.

    High expression of angiotensin-converting enzyme 2 receptor (ACE-2), transmembrane protease serine (TMPRSS), and P-selectin in platelets lead to thrombosis formation in COVID-19 patients.
    Waggiallah HA, Eltayeb MM, Hjazi AM, Elmosaad YM.

    03/22/2024
    PSGL-1 decorated with sialyl Lewis[a/x] promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement.

    PSGL-1 decorated with sialyl Lewis(a/x) promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement.
    O'Dwyer M, Kirkham-McCarthy L, Cerreto M, Foà R, Natoni A., Free PMC Article

    01/30/2024
    Association of the rs3917647 polymorphism of the SELP gene with malnutrition in gastric cancer.

    Association of the rs3917647 polymorphism of the SELP gene with malnutrition in gastric cancer.
    Fu L, Lei C, Chen Y, Xu X, Wu B, Dong L, Ye X, Zheng L, Gong D.

    11/20/2023
    Clinical significance of elevated soluble T-cell immunoglobulin and mucin domain 1 and soluble P-selectin in individuals with obstructive sleep apnea-hypopnea syndrome.

    Clinical significance of elevated soluble T-cell immunoglobulin and mucin domain 1 and soluble P-selectin in individuals with obstructive sleep apnea-hypopnea syndrome.
    Fan H, Liu Y, Zhang X, Sun J, Lin N., Free PMC Article

    11/14/2023
    Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand.

    Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand.
    Takada Y, Fujita M, Takada YK., Free PMC Article

    09/29/2023
    SARS-CoV-2 Spike Proteins and Cell-Cell Communication Induce P-Selectin and Markers of Endothelial Injury, NETosis, and Inflammation in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for the Pathogenesis of COVID-19 Coagulopathy.

    SARS-CoV-2 Spike Proteins and Cell-Cell Communication Induce P-Selectin and Markers of Endothelial Injury, NETosis, and Inflammation in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for the Pathogenesis of COVID-19 Coagulopathy.
    Bhargavan B, Kanmogne GD., Free PMC Article

    08/30/2023
    Plasma levels of P-selectin and future risk of incident venous thromboembolism.

    Plasma levels of P-selectin and future risk of incident venous thromboembolism.
    Swamy S, Ueland T, Hansen JB, Snir O, Brækkan SK.

    08/28/2023
    Increased Platelet Activation demonstrated by Elevated CD36 and P-Selectin Expression in 1-Year Post-Recovered COVID-19 Patients.

    Increased Platelet Activation demonstrated by Elevated CD36 and P-Selectin Expression in 1-Year Post-Recovered COVID-19 Patients.
    Wang SSY, Chee K, Wong SW, Tan GB, Ang H, Leung BP, Tan CW, Ramanathan K, Dalan R, Cheung C, Lye DC, Young BE, Yap ES, Chia YW, Fan BE, COVID-19 Clotting and Bleeding Investigators.

    06/22/2023
    Differentiated serum levels of Kruppel-like factors 2 and 4, sP-selectin, and sE-selectin in patients with gestational diabetes mellitus.

    Differentiated serum levels of Krüppel-like factors 2 and 4, sP-selectin, and sE-selectin in patients with gestational diabetes mellitus.
    Zhang H, Chen Z, Wang X.

    03/7/2023
    The role of P-selectin in cancer-associated thrombosis and beyond.

    The role of P-selectin in cancer-associated thrombosis and beyond.
    Yeini E, Satchi-Fainaro R.

    10/15/2022
    Prognostic Significance of Platelet Activation Marker CD62P in Hospitalized Covid-19 Patients.

    Prognostic Significance of Platelet Activation Marker CD62P in Hospitalized Covid-19 Patients.
    Eldahshan M, Byomy MA, Alsadek AM, Hassan MM, Eltrawy HH, Abdelwahab MK, Ali WDK, Eliwa A.

    10/1/2022
    Association of Thr715Pro P-Selectin Gene Polymorphism in Diabetic Retinopathy in North Indian Population: A Prospective Clinical Study.

    Association of Thr715Pro P-Selectin Gene Polymorphism in Diabetic Retinopathy in North Indian Population: A Prospective Clinical Study.
    Sharma R, Kant S, Mishra D, Srivastav T, Singh H.

    08/27/2022
    Clinical Significance of PAC-1, CD62P, and Platelet-Leukocyte Aggregates in Acute Ischemic Stroke.

    Clinical Significance of PAC-1, CD62P, and Platelet-Leukocyte Aggregates in Acute Ischemic Stroke.
    Zhang Y, Ma Z, Liu Q, Qiao Q, Wu Q, Zou X, Xing Y, Zhang B.

    04/16/2022
    Flow adhesion of whole blood to P-selectin: a prognostic biomarker for vaso-occlusive crisis in sickle cell disease.

    Flow adhesion of whole blood to P-selectin: a prognostic biomarker for vaso-occlusive crisis in sickle cell disease.
    Hines PC, Callaghan MU, Zaidi AU, Gao X, Liu K, White J, Tarasev M., Free PMC Article

    12/18/2021
    Plasma P-selectin is an early marker of thromboembolism in COVID-19.

    Plasma P-selectin is an early marker of thromboembolism in COVID-19.
    Fenyves BG, Mehta A, MGH COVID-19 Collection & Processing Team, Kays KR, Beakes C, Margolin J, Goldberg MB, Hacohen N, Filbin MR., Free PMC Article

    12/11/2021
    Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study.

    Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study.
    Izzi B, Gialluisi A, Gianfagna F, Orlandi S, De Curtis A, Magnacca S, Costanzo S, Di Castelnuovo A, Donati MB, de Gaetano G, Hoylaerts MF, Cerletti C, Iacoviello L, On Behalf Of The Moli-Family Study Investigators., Free PMC Article

    12/4/2021
    SELP Asp603Asn and severe thrombosis in COVID-19 males.

    SELP Asp603Asn and severe thrombosis in COVID-19 males.
    Fallerini C, Daga S, Benetti E, Picchiotti N, Zguro K, Catapano F, Baroni V, Lanini S, Bucalossi A, Marotta G, Colombo F, Baldassarri M, Fava F, Beligni G, Di Sarno L, Alaverdian D, Palmieri M, Croci S, Isidori AM, Furini S, Frullanti E, GEN-COVID Multicenter Study, Renieri A, Mari F., Free PMC Article

    08/28/2021
    Relationship of Platelet Glycoprotein IIb/IIIa and CD62P With Hypercoagulable State After Oncologic Surgery.

    Relationship of Platelet Glycoprotein IIb/IIIa and CD62P With Hypercoagulable State After Oncologic Surgery.
    Zhong X, Cao Z, Song J, Liu Y, Guo Q., Free PMC Article

    07/31/2021
    Soluble P-selectin as a potential diagnostic and prognostic biomarker for COVID-19 disease: A case-control study.

    Soluble P-selectin as a potential diagnostic and prognostic biomarker for COVID-19 disease: A case-control study.
    Karsli E, Sabirli R, Altintas E, Canacik O, Sabirli GT, Kaymaz B, Kurt Ö, Koseler A., Free PMC Article

    06/26/2021
    Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer.

    Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer.
    DuRoss AN, Landry MR, Thomas CR Jr, Neufeld MJ, Sun C., Free PMC Article

    06/26/2021
    A Combined Activity of Thrombin and P-Selectin Is Essential for Platelet Activation by Pancreatic Cancer Cells.

    A Combined Activity of Thrombin and P-Selectin Is Essential for Platelet Activation by Pancreatic Cancer Cells.
    Haschemi R, Gockel LM, Bendas G, Schlesinger M., Free PMC Article

    06/12/2021
    Circulating P-Selectin Glycoprotein Ligand 1 and P-Selectin Levels in Obstructive Sleep Apnea Patients.

    Circulating P-Selectin Glycoprotein Ligand 1 and P-Selectin Levels in Obstructive Sleep Apnea Patients.
    Horváth P, Lázár Z, Gálffy G, Puskás R, Kunos L, Losonczy G, Mészáros M, Tárnoki ÁD, Tárnoki DL, Bikov A., Free PMC Article

    06/5/2021
    Putative functional non-coding polymorphisms in SELP significantly modulate sP-selectin levels, arterial stiffness and type 2 diabetes mellitus susceptibility.

    Putative functional non-coding polymorphisms in SELP significantly modulate sP-selectin levels, arterial stiffness and type 2 diabetes mellitus susceptibility.
    Kaur R, Singh J, Kapoor R, Kaur M., Free PMC Article

    03/20/2021
    The Ser290Asn and Thr715Pro Polymorphisms of the SELP Gene Are Associated with A Lower Risk of Developing Acute Coronary Syndrome and Low Soluble P-Selectin Levels in A Mexican Population (double dagger).

    The Ser290Asn and Thr715Pro Polymorphisms of the SELP Gene Are Associated with A Lower Risk of Developing Acute Coronary Syndrome and Low Soluble P-Selectin Levels in A Mexican Population (‡).
    Herrera-Maya G, Vargas-Alarcón G, Pérez-Méndez O, Posadas-Sánchez R, Masso F, Juárez-Cedillo T, Escobedo G, Vázquez-Montero A, Fragoso JM., Free PMC Article

    03/13/2021
    P-selectin (CD62P) and soluble TREM-like transcript-1 (sTLT-1) are associated with coronary artery disease: a case control study.

    P-selectin (CD62P) and soluble TREM-like transcript-1 (sTLT-1) are associated with coronary artery disease: a case control study.
    Shen L, Yang T, Xia K, Yan Z, Tan J, Li L, Qin Y, Shi W., Free PMC Article

    01/16/2021
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