EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis. | EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis. Wang R, Lv C, Li D, Song Y, Yan Z. | 08/21/2024 |
Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia. | Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia. Guo L, Ren H, Fan S, Chao X, Liu M, Guan H, Wang J., Free PMC Article | 02/26/2024 |
EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway. | EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway. Xie C, Zhou M, Lin J, Wu Z, Ding S, Luo J, Zhan Z, Cai Y, Xue S, Song Y., Free PMC Article | 05/1/2021 |
Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus. | Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus. Gao Q, Yang C, Ren C, Zhang S, Gao X, Jin M, Chen H, Ma W, Zhou H., Free PMC Article | 03/20/2021 |
EEF1D is upregulated in osteosarcoma and plays a tumor promoting role by facilitating Akt-mTOR and Akt-Bad signaling pathways. Accordingly, EEF1D is a potential target for cancer therapy. | EEF1D overexpression promotes osteosarcoma cell proliferation by facilitating Akt-mTOR and Akt-bad signaling. Cheng DD, Li SJ, Zhu B, Zhou SM, Yang QC., Free PMC Article | 05/11/2019 |
the loss of function variants exclusively targeting the long EEF1D isoform may explicate the ARID phenotype through the heat shock response pathway, rather than interfering with the canonical translational elongation. | Biallelic loss of EEF1D function links heat shock response pathway to autosomal recessive intellectual disability. Ugur Iseri SA, Yucesan E, Tuncer FN, Calik M, Kesim Y, Altiokka Uzun G, Ozbek U. | 04/20/2019 |
eukaryotic translation elongation factor 1delta knockdown in oral squamous cell carcinoma reduced cell proliferation and induced EMT (epithelial-mesenchymal transition) phenotypes | EEF1D modulates proliferation and epithelial-mesenchymal transition in oral squamous cell carcinoma. Flores IL, Kawahara R, Miguel MC, Granato DC, Domingues RR, Macedo CC, Carnielli CM, Yokoo S, Rodrigues PC, Monteiro BV, Oliveira CE, Salmon CR, Nociti FH Jr, Lopes MA, Santos-Silva A, Winck FV, Coletta RD, Paes Leme AF. | 04/15/2017 |
our results demonstrate that EEF1D is a bona fide physiological CK2 substrate for CK2 phosphorylation | Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2. Gyenis L, Duncan JS, Turowec JP, Bretner M, Litchfield DW., Free PMC Article | 03/10/2012 |
Taken together, our data suggest EFF1D functions as a novel negative regulator of SIAH-1 | Eukaryotic translation elongation factor 1 delta inhibits the ubiquitin ligase activity of SIAH-1. Wu H, Shi Y, Lin Y, Qian W, Yu Y, Huo K. | 02/25/2012 |
overexpression is positively correlated with malignant transformation of 16HBE cells induced by CdC12, but is not correlated with DNA mutations | Alternative expression and sequence of human elongation factor-1 delta during malignant transformation of human bronchial epithelial cells induced by cadmium chloride. Lei YX, Wang M, Wei L, Lu X, Lin HZ. | 07/12/2010 |
Repression of deltaEF1 plays a key role in mediating BMP-6-induced transcriptional activation of E-cadherin in breast cancer cells. | BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells. Yang S, Du J, Wang Z, Yuan W, Qiao Y, Zhang M, Zhang J, Gao S, Yin J, Sun B, Zhu T., Free PMC Article | 01/21/2010 |
Increased EF-1 delta mRNA expression is associated with lymph node metastases and advanced disease stages in esophageal carcinoma | Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma. Ogawa K, Utsunomiya T, Mimori K, Tanaka Y, Tanaka F, Inoue H, Murayama S, Mori M., Free PMC Article | 01/21/2010 |
Gain of 8q-mapped EF-1 delta is associated with adverse outcome in Medulloblastoma. | Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. De Bortoli M, Castellino RC, Lu XY, Deyo J, Sturla LM, Adesina AM, Perlaky L, Pomeroy SL, Lau CC, Man TK, Rao PH, Kim JY., Free PMC Article | 01/21/2010 |
Interaction between HrHRF and EF-1delta taken with some of the recently published information concerning the TCTP (HrHRF) mentioned above suggest a possible intracellular role for TCTP/HrHRF. | Identification of the interaction between the human recombinant histamine releasing factor/translationally controlled tumor protein and elongation factor-1 delta (also known as eElongation factor-1B beta). Langdon JM, Vonakis BM, MacDonald SM. | 01/21/2010 |
These results further confirm that overexpression of TEF-1 delta is oncogenic and the antisense TEF-1 delta mRNA expression reverses its oncogenic potential. | Blocking the translation elongation factor-1 delta with its antisense mRNA results in a significant reversal of its oncogenic potential. Lei YX, Chen JK, Wu ZL. | 01/21/2010 |