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    CBR3-AS1 CBR3 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100506428, updated on 30-Oct-2023

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LncRNA-CBR3-AS1 promotes and enhances the malignancy of ulcerative colitis via targeting miRNA-145-5p/FN1.

    LncRNA-CBR3-AS1 promotes and enhances the malignancy of ulcerative colitis via targeting miRNA-145-5p/FN1.
    Cao J, Zhao Q, Jia Q, Li Y.

    09/25/2023
    LncRNA CBR3-AS1 predicts a poor prognosis and promotes cervical cancer progression through the miR-3163/LASP1 pathway.

    LncRNA CBR3-AS1 predicts a poor prognosis and promotes cervical cancer progression through the miR-3163/LASP1 pathway.
    Cai Y, Huang Y, Zhang J, Liu X, Zhao F, Zhang K, Xu S, Yang Y, Huang H, Gao Y.

    01/14/2023
    Long Non-coding RNA CBR3 Antisense RNA 1 is Downregulated in Colorectal Cancer and Inhibits miR-29a-Mediated Cell Migration and Invasion.

    Long Non-coding RNA CBR3 Antisense RNA 1 is Downregulated in Colorectal Cancer and Inhibits miR-29a-Mediated Cell Migration and Invasion.
    Yang M, Chen W, Liu H, Yu L, Tang M, Liu Y.

    07/2/2022
    Long Non-Coding RNAs Expression in Breast Cancer: CBR3-AS1 LncRNA as a Sensitive Biomarker.

    Long Non-Coding RNAs Expression in Breast Cancer: CBR3-AS1 LncRNA as a Sensitive Biomarker.
    Torkashvand S, Basi A, Ajdarkosh H, Rakhshani N, Nafisi N, Mowla SJ, Moghadas A, Mohammadipour M, Karbalaie Niya MH., Free PMC Article

    12/25/2021
    LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway.

    LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway.
    Zhang M, Wang Y, Jiang L, Song X, Zheng A, Gao H, Wei M, Zhao L., Free PMC Article

    09/11/2021
    LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis.

    LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis.
    Cui Z, Gao H, Yan N, Dai Y, Wang H, Wang M, Wang J, Zhang D, Sun P, Qi T, Wang Q, Kang W, Jin X., Free PMC Article

    07/31/2021
    LncRNA PlncRNA-1 participates in rheumatoid arthritis by regulating transforming growth factor beta1.

    LncRNA PlncRNA-1 participates in rheumatoid arthritis by regulating transforming growth factor β1.
    Wang Y, Li G, Guo W, Ji B, Aisikeerbayi A, Boratibai Y, Cao L.

    07/31/2021
    Long noncoding RNA CBR3 antisense RNA 1 promotes the aggressive phenotypes of nonsmallcell lung cancer by sponging microRNA5093p and competitively upregulating HDAC9 expression.

    Long noncoding RNA CBR3 antisense RNA 1 promotes the aggressive phenotypes of non‑small‑cell lung cancer by sponging microRNA‑509‑3p and competitively upregulating HDAC9 expression.
    Guan Y, Yang J, Liu X, Chu L., Free PMC Article

    07/10/2021
    Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis.

    Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis.
    Kang W, Wang Q, Dai Y, Wang H, Wang M, Wang J, Zhang D, Sun P, Qi T, Jin X, Cui Z., Free PMC Article

    04/13/2021
    patients with advanced stage retinoblastoma had higher levels of PlncRNA-1 expression than patients with early stage retinoblastoma. There was an inverse correlation between PlncRNA-1 expression and CBR3 expression in retinoblastoma tissues, and PlncRNA-1 negatively regulated mRNA and protein expressions of CBR3.

    PlncRNA-1 is overexpressed in retinoblastoma and regulates retinoblastoma cell proliferation and motility through modulating CBR3.
    Wang S, Liu J, Yang Y, Hao F, Zhang L.

    08/3/2019
    High expression of Plnc RNA-1 promotes the progression of colorectal cancer.

    High expression of Plnc RNA-1 promotes the progression of colorectal cancer.
    Song B, Jia Y.

    08/3/2019
    These results suggest that the PlncRNA-1/miR-204/ Wnt/beta-catenin regulatory network may shed light on tumorigenesis in colorectal cancer.

    Long non-coding RNA PlncRNA-1 promotes cell proliferation and hepatic metastasis in colorectal cancer.
    Jia GQ, Zhang MM, Wang K, Zhao GP, Pang MH, Chen ZY.

    05/18/2019
    LncRNA PlncRNA-1 overexpression inhibits the growth of breast cancer by upregulating TGF-beta1 and downregulating PHGDH. PlncRNA-1 was downregulated in primary breast tumor tissues comparing with adjacent healthy tissues.

    LncRNA PlncRNA-1 overexpression inhibits the growth of breast cancer by upregulating TGF-β1 and downregulating PHGDH.
    Li Q, Gao H, Zhou S, Liao Y.

    11/17/2018
    There was no association between LncRNA CBR3-AS1 (also known as PlncRNA-1), and CBR3 expression in osteosarcoma tissues. In conclusion, lncRNA CBR3-AS1 serves an independent poor prognostic factor for osteosarcoma patients.

    LncRNA CBR3-AS1 predicts unfavorable prognosis and promotes tumorigenesis in osteosarcoma.
    Zhang Y, Meng W, Cui H.

    10/13/2018
    PlncRNA-1 knockdown remarkably reduced cell proliferation, migration, and invasion and promoted cell apoptosis in vitro. In vivo xenograft experiments showed that PlncRNA-1 inhibition significantly suppressed tumor growth.

    Long Noncoding RNA PlncRNA-1 Promotes Colorectal Cancer Cell Progression by Regulating the PI3K/Akt Signaling Pathway.
    Song W, Mei JZ, Zhang M., Free PMC Article

    09/1/2018
    PlncRNA-1 is an oncogene that regulates the cell cycle, cyclin-D1 and EMT in prostate cancer cells through the TGF-beta1 pathway.

    Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer.
    Jin Y, Cui Z, Li X, Jin X, Peng J., Free PMC Article

    03/10/2018
    In conclusion, PlncRNA-1 and TUG1 genes may play a critical role in gastric cancer (GC) progression and may serve as potential diagnostic biomarkers in GC patients

    Aberrant expression of PlncRNA-1 and TUG1: potential biomarkers for gastric cancer diagnosis and clinically monitoring cancer progression.
    Baratieh Z, Khalaj Z, Honardoost MA, Emadi-Baygi M, Khanahmad H, Salehi M, Nikpour P.

    01/27/2018
    Data suggest that long noncoding RNA PlncRNA1 and microRNA miR-34c bound together to regulate the expressions of MAZ, ZO-1 and occludin.

    MiR-34c and PlncRNA1 mediated the function of intestinal epithelial barrier by regulating tight junction proteins in inflammatory bowel disease.
    Chen T, Xue H, Lin R, Huang Z.

    06/24/2017
    PlncRNA-1 expression is up-regulated in human Hepatocellular Carcinoma tissues and correlated with tumor stage and metastasis.

    Upregulation of Long Non-Coding RNA PlncRNA-1 Promotes Metastasis and Induces Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma.
    Dong L, Ni J, Hu W, Yu C, Li H.

    11/12/2016
    Functional analysis revealed that miR-34c and miR-297 overexpression down-regulated AR expression and inhibited the expression of downstream AR targets and that PlncRNA-1 overexpression rescued these effects.

    A feed-forward regulatory loop between androgen receptor and PlncRNA-1 promotes prostate cancer progression.
    Fang Z, Xu C, Li Y, Cai X, Ren S, Liu H, Wang Y, Wang F, Chen R, Qu M, Wang Y, Zhu Y, Zhang W, Shi X, Yao J, Gao X, Hou J, Xu C, Sun Y.

    07/16/2016
    PlncRNA-1 plays an important role in esophageal squamous cell carcinoma cell proliferation. Overexpression of PlncRNA-1 is correlated with advanced tumor stage and lymph node metastasis.

    Upregulation of the long non-coding RNA PlncRNA-1 promotes esophageal squamous carcinoma cell proliferation and correlates with advanced clinical stage.
    Wang CM, Wu QQ, Li SQ, Chen FJ, Tuo L, Xie HW, Tong YS, Ji L, Zhou GZ, Cao G, Wu M, Lv J, Shi WH, Cao XF.

    04/19/2014
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