LncRNA-CBR3-AS1 promotes and enhances the malignancy of ulcerative colitis via targeting miRNA-145-5p/FN1. | LncRNA-CBR3-AS1 promotes and enhances the malignancy of ulcerative colitis via targeting miRNA-145-5p/FN1. Cao J, Zhao Q, Jia Q, Li Y. | 09/25/2023 |
LncRNA CBR3-AS1 predicts a poor prognosis and promotes cervical cancer progression through the miR-3163/LASP1 pathway. | LncRNA CBR3-AS1 predicts a poor prognosis and promotes cervical cancer progression through the miR-3163/LASP1 pathway. Cai Y, Huang Y, Zhang J, Liu X, Zhao F, Zhang K, Xu S, Yang Y, Huang H, Gao Y. | 01/14/2023 |
Long Non-coding RNA CBR3 Antisense RNA 1 is Downregulated in Colorectal Cancer and Inhibits miR-29a-Mediated Cell Migration and Invasion. | Long Non-coding RNA CBR3 Antisense RNA 1 is Downregulated in Colorectal Cancer and Inhibits miR-29a-Mediated Cell Migration and Invasion. Yang M, Chen W, Liu H, Yu L, Tang M, Liu Y. | 07/2/2022 |
Long Non-Coding RNAs Expression in Breast Cancer: CBR3-AS1 LncRNA as a Sensitive Biomarker. | Long Non-Coding RNAs Expression in Breast Cancer: CBR3-AS1 LncRNA as a Sensitive Biomarker. Torkashvand S, Basi A, Ajdarkosh H, Rakhshani N, Nafisi N, Mowla SJ, Moghadas A, Mohammadipour M, Karbalaie Niya MH., Free PMC Article | 12/25/2021 |
LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway. | LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway. Zhang M, Wang Y, Jiang L, Song X, Zheng A, Gao H, Wei M, Zhao L., Free PMC Article | 09/11/2021 |
LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis. | LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis. Cui Z, Gao H, Yan N, Dai Y, Wang H, Wang M, Wang J, Zhang D, Sun P, Qi T, Wang Q, Kang W, Jin X., Free PMC Article | 07/31/2021 |
LncRNA PlncRNA-1 participates in rheumatoid arthritis by regulating transforming growth factor beta1. | LncRNA PlncRNA-1 participates in rheumatoid arthritis by regulating transforming growth factor β1. Wang Y, Li G, Guo W, Ji B, Aisikeerbayi A, Boratibai Y, Cao L. | 07/31/2021 |
Long noncoding RNA CBR3 antisense RNA 1 promotes the aggressive phenotypes of nonsmallcell lung cancer by sponging microRNA5093p and competitively upregulating HDAC9 expression. | Long noncoding RNA CBR3 antisense RNA 1 promotes the aggressive phenotypes of non‑small‑cell lung cancer by sponging microRNA‑509‑3p and competitively upregulating HDAC9 expression. Guan Y, Yang J, Liu X, Chu L., Free PMC Article | 07/10/2021 |
Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis. | Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis. Kang W, Wang Q, Dai Y, Wang H, Wang M, Wang J, Zhang D, Sun P, Qi T, Jin X, Cui Z., Free PMC Article | 04/13/2021 |
patients with advanced stage retinoblastoma had higher levels of PlncRNA-1 expression than patients with early stage retinoblastoma. There was an inverse correlation between PlncRNA-1 expression and CBR3 expression in retinoblastoma tissues, and PlncRNA-1 negatively regulated mRNA and protein expressions of CBR3. | PlncRNA-1 is overexpressed in retinoblastoma and regulates retinoblastoma cell proliferation and motility through modulating CBR3. Wang S, Liu J, Yang Y, Hao F, Zhang L. | 08/3/2019 |
High expression of Plnc RNA-1 promotes the progression of colorectal cancer. | High expression of Plnc RNA-1 promotes the progression of colorectal cancer. Song B, Jia Y. | 08/3/2019 |
These results suggest that the PlncRNA-1/miR-204/ Wnt/beta-catenin regulatory network may shed light on tumorigenesis in colorectal cancer. | Long non-coding RNA PlncRNA-1 promotes cell proliferation and hepatic metastasis in colorectal cancer. Jia GQ, Zhang MM, Wang K, Zhao GP, Pang MH, Chen ZY. | 05/18/2019 |
LncRNA PlncRNA-1 overexpression inhibits the growth of breast cancer by upregulating TGF-beta1 and downregulating PHGDH. PlncRNA-1 was downregulated in primary breast tumor tissues comparing with adjacent healthy tissues. | LncRNA PlncRNA-1 overexpression inhibits the growth of breast cancer by upregulating TGF-β1 and downregulating PHGDH. Li Q, Gao H, Zhou S, Liao Y. | 11/17/2018 |
There was no association between LncRNA CBR3-AS1 (also known as PlncRNA-1), and CBR3 expression in osteosarcoma tissues. In conclusion, lncRNA CBR3-AS1 serves an independent poor prognostic factor for osteosarcoma patients. | LncRNA CBR3-AS1 predicts unfavorable prognosis and promotes tumorigenesis in osteosarcoma. Zhang Y, Meng W, Cui H. | 10/13/2018 |
PlncRNA-1 knockdown remarkably reduced cell proliferation, migration, and invasion and promoted cell apoptosis in vitro. In vivo xenograft experiments showed that PlncRNA-1 inhibition significantly suppressed tumor growth. | Long Noncoding RNA PlncRNA-1 Promotes Colorectal Cancer Cell Progression by Regulating the PI3K/Akt Signaling Pathway. Song W, Mei JZ, Zhang M., Free PMC Article | 09/1/2018 |
PlncRNA-1 is an oncogene that regulates the cell cycle, cyclin-D1 and EMT in prostate cancer cells through the TGF-beta1 pathway. | Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer. Jin Y, Cui Z, Li X, Jin X, Peng J., Free PMC Article | 03/10/2018 |
In conclusion, PlncRNA-1 and TUG1 genes may play a critical role in gastric cancer (GC) progression and may serve as potential diagnostic biomarkers in GC patients | Aberrant expression of PlncRNA-1 and TUG1: potential biomarkers for gastric cancer diagnosis and clinically monitoring cancer progression. Baratieh Z, Khalaj Z, Honardoost MA, Emadi-Baygi M, Khanahmad H, Salehi M, Nikpour P. | 01/27/2018 |
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR-34c bound together to regulate the expressions of MAZ, ZO-1 and occludin. | MiR-34c and PlncRNA1 mediated the function of intestinal epithelial barrier by regulating tight junction proteins in inflammatory bowel disease. Chen T, Xue H, Lin R, Huang Z. | 06/24/2017 |
PlncRNA-1 expression is up-regulated in human Hepatocellular Carcinoma tissues and correlated with tumor stage and metastasis. | Upregulation of Long Non-Coding RNA PlncRNA-1 Promotes Metastasis and Induces Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma. Dong L, Ni J, Hu W, Yu C, Li H. | 11/12/2016 |
Functional analysis revealed that miR-34c and miR-297 overexpression down-regulated AR expression and inhibited the expression of downstream AR targets and that PlncRNA-1 overexpression rescued these effects. | A feed-forward regulatory loop between androgen receptor and PlncRNA-1 promotes prostate cancer progression. Fang Z, Xu C, Li Y, Cai X, Ren S, Liu H, Wang Y, Wang F, Chen R, Qu M, Wang Y, Zhu Y, Zhang W, Shi X, Yao J, Gao X, Hou J, Xu C, Sun Y. | 07/16/2016 |
PlncRNA-1 plays an important role in esophageal squamous cell carcinoma cell proliferation. Overexpression of PlncRNA-1 is correlated with advanced tumor stage and lymph node metastasis. | Upregulation of the long non-coding RNA PlncRNA-1 promotes esophageal squamous carcinoma cell proliferation and correlates with advanced clinical stage. Wang CM, Wu QQ, Li SQ, Chen FJ, Tuo L, Xie HW, Tong YS, Ji L, Zhou GZ, Cao G, Wu M, Lv J, Shi WH, Cao XF. | 04/19/2014 |