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    neurl4 neuralized E3 ubiquitin protein ligase 4 [ Danio rerio (zebrafish) ]

    Gene ID: 555331, updated on 17-Aug-2024

    Summary

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    Official Symbol
    neurl4provided by ZNC
    Official Full Name
    neuralized E3 ubiquitin protein ligase 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100318-4
    See related
    Ensembl:ENSDARG00000078127 AllianceGenome:ZFIN:ZDB-GENE-100318-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:eu380
    Summary
    Predicted to enable ubiquitin protein ligase activity. Orthologous to human NEURL4 (neuralized E3 ubiquitin protein ligase 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (22449180..22509385, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (22327961..22387923, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 15b Neighboring gene high density lipoprotein binding protein b Neighboring gene sex hormone-binding globulin Neighboring gene zinc finger and BTB domain containing 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    neuralized E3 ubiquitin protein ligase 4; neuralized-like protein 4
    Names
    neuralized homolog 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      22449180..22509385 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480311.1 → XP_021335986.1  neuralized-like protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B331
      Conserved Domains (1) summary
      cd12887
      Location:553 → 713
      SPRY_NHR_like; SPRY domain in neuralized homology repeat

    2. XM_021480310.1 → XP_021335985.1  neuralized-like protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8N7T6V4, E7FDT2
      Related
      ENSDARP00000101391.2, ENSDART00000109707.4
      Conserved Domains (1) summary
      cd12887
      Location:553 → 713
      SPRY_NHR_like; SPRY domain in neuralized homology repeat

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394839.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      391279..451484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005156224.4 → XP_005156281.1  neuralized-like protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B331
      Conserved Domains (1) summary
      cd12887
      Location:553 → 713
      SPRY_NHR_like; SPRY domain in neuralized homology repeat

    2. XM_677822.9 → XP_682914.5  neuralized-like protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8N7T6V4, E7FDT2
      Conserved Domains (1) summary
      cd12887
      Location:553 → 713
      SPRY_NHR_like; SPRY domain in neuralized homology repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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