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    CG8159 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41040, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG8159provided by FlyBase
    Primary source
    FLYBASE:FBgn0037619
    Locus tag
    Dmel_CG8159
    See related
    AllianceGenome:FB:FBgn0037619
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8159
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG8159 in Genome Data Viewer
    Location:
    85A9-85A9; 3-48 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8726854..8728370)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4552576..4554092)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene numerous disordered muscles Neighboring gene ouija board Neighboring gene ranshi Neighboring gene Motif 1 Binding Protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cooperative Control of Ecdysone Biosynthesis in Drosophila by Transcription Factors Séance, Ouija Board, and Molting Defective. Uryu O, et al. Genetics, 2018 Feb. PMID 29187506, Free PMC Article
    2. Mago Nashi, Tsunagi/Y14, and Ranshi form a complex that influences oocyte differentiation in Drosophila melanogaster. Lewandowski JP, et al. Dev Biol, 2010 Mar 15. PMID 20045686, Free PMC Article
    3. Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila. Bonchuk A, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33638995, Free PMC Article
    4. Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid. Li M, et al. PLoS One, 2023. PMID 36595500, Free PMC Article
    5. Genomic expansion and clustering of ZAD-containing C2H2 zinc-finger genes in Drosophila. Chung HR, et al. EMBO Rep, 2002 Dec. PMID 12446571, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8159-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8726854..8728370
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141566.2 → NP_649823.2  uncharacterized protein Dmel_CG8159 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649823.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQX2, Q9VHM5
      Conserved Domains (4) summary
      smart00868
      Location:5 → 78
      zf-AD; Zinc-finger associated domain (zf-AD)
      COG5048
      Location:197 → 322
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:250 → 270
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:291 → 315
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQX2 Q8MQX2
    Q9VHM5 Q9VHM5

    Gene LinkOut

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