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    CG31915 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 319025, updated on 28-Oct-2024

    Summary

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    Official Symbol
    CG31915provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051915
    Locus tag
    Dmel_CG31915
    See related
    AllianceGenome:FB:FBgn0051915
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6922; Dmel\CG31915
    Summary
    Predicted to enable procollagen galactosyltransferase activity. Predicted to be involved in positive regulation of collagen fibril organization. Predicted to be located in endoplasmic reticulum lumen. Is expressed in adult head. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Orthologous to several human genes including COLGALT1 (collagen beta(1-O)galactosyltransferase 1) and COLGALT2 (collagen beta(1-O)galactosyltransferase 2). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See CG31915 in Genome Data Viewer
    Location:
    25E5-25E5; 2-17 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5528123..5530682)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5528123..5530682)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44793 Neighboring gene Elongator complex protein 4 Neighboring gene Chromosome associated protein D3 Neighboring gene Cytochrome c oxidase copper chaperone COX11 Neighboring gene Coenzyme Q6 Neighboring gene tombola Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions. Sakaidani Y, et al. Nat Commun, 2011 Dec 13. PMID 22158438
    2. Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early. Jiang J, et al. Development, 2007 Apr. PMID 17360778, Free PMC Article
    3. Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Rehwinkel J, et al. Nat Struct Mol Biol, 2004 Jun. PMID 15133499
    4. A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Baumbach J, et al. Cell Metab, 2014 Feb 4. PMID 24506874
    5. Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Engström PG, et al. Genome Res, 2007 Dec. PMID 17989259, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables procollagen galactosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables procollagen galactosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of collagen fibril organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum lumen ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31915-PA
    NP_723087.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5528123..5530682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164645.3 → NP_723087.1  uncharacterized protein Dmel_CG31915 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723087.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9UNF8, Q8IPK4
      Related
      FBpp0078732
      Conserved Domains (2) summary
      cd06532
      Location:334 → 515
      Glyco_transf_25; Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of ...
      cl11394
      Location:32 → 146
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IPK4.1 Q8IPK4

    Gene LinkOut

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