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    GTF2IRD1 GTF2I repeat domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 9569, updated on 28-Oct-2024

    Summary

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    Official Symbol
    GTF2IRD1provided by HGNC
    Official Full Name
    GTF2I repeat domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:4661
    See related
    Ensembl:ENSG00000006704 MIM:604318; AllianceGenome:HGNC:4661
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1
    Summary
    The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
    Expression
    Ubiquitous expression in thyroid (RPKM 6.1), esophagus (RPKM 4.7) and 23 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See GTF2IRD1 in Genome Data Viewer
    Location:
    7q11.23
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (74453906..74602605)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (75656184..75805371)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (73868236..74016931)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986742 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73696998-73697628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26158 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18277 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73704091-73704735 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73704736-73705379 Neighboring gene Sharpr-MPRA regulatory region 1083 Neighboring gene NFE2L2 motif-containing MPRA enhancer 193 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:73722243-73722881 Neighboring gene CAP-Gly domain containing linker protein 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73778293-73779164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73779165-73780034 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73786483-73787481 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73794630-73795130 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73795131-73795631 Neighboring gene Sharpr-MPRA regulatory region 11240 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:73810181-73810370 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73819861-73820723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73818996-73819860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18279 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73843950-73844923 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73848492-73849112 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73849734-73850353 Neighboring gene CAGE-defined high expression enhancer upstream of GTF2IRD1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18280 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18281 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26159 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73892244-73892825 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73892826-73893408 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26160 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26161 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26162 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73909445-73910043 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73919312-73919812 Neighboring gene RNA, 5S ribosomal pseudogene 233 Neighboring gene Williams-Beuren syndrome chromosome region 23 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73995345-73995846 Neighboring gene Sharpr-MPRA regulatory region 2459 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:74001529-74002116 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:74002117-74002703 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26165 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18282 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:74031162-74031727 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:74031728-74032292 Neighboring gene microRNA 10525 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18283 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18284 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26166 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26168 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18288 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18287 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26167 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26169 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26170 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:74075507-74076155 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26173 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26174 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26175 Neighboring gene GTF2I antisense RNA 1 Neighboring gene general transcription factor IIi Neighboring gene Williams-Beuren syndrome medial block B recombination region Neighboring gene PHB1 pseudogene 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Identification of a putative transcription factor gene (WBSCR11) that is commonly deleted in Williams-Beuren syndrome. Osborne LR, et al. Genomics, 1999 Apr 15. PMID 10198167
    2. A transcription factor involved in skeletal muscle gene expression is deleted in patients with Williams syndrome. Tassabehji M, et al. Eur J Hum Genet, 1999 Oct-Nov. PMID 10573005
    3. Characterization and gene structure of a novel retinoblastoma-protein-associated protein similar to the transcription regulator TFII-I. Yan X, et al. Biochem J, 2000 Feb 1. PMID 10642537, Free PMC Article
    4. GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer. Zhuang H, et al. Biosci Rep, 2020 Sep 30. PMID 32936232, Free PMC Article
    5. GTF2IRD1 regulates transcription by binding an evolutionarily conserved DNA motif 'GUCE'. Thompson PD, et al. FEBS Lett, 2007 Mar 20. PMID 17346708

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer.
      Title: GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer.
    2. Study showed that GTF2IRD1 was overexpressed due to copy number amplification at Ch.7q in colorectal cancer (CRC). The expression of GTF2IRD1 was positively associated with the malignant pathological phenotype. Furthermore, high expression of GTF2IRD1 was an independent poor prognostic factor in CRC. Mechanistically, GTF2IRD1 promoted cell cycle progression by downregulation of TGFbetaR2 in CRC.
      Title: GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor-suppressor gene TGFβR2 in colorectal cancer.
    3. Among 110 SNPs within the 7q11.23 William's Syndrome (WS) chromosomal region, we found one associated locus located at GTF2IRD1, which has been implicated in animal models of WS.
      Title: Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes.
    4. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.
      Title: An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.
    5. Study demonstrates a significant association between SLE in Chinese Han population and the GTF2I rs117026326 T allele/GTF2IRD1 rs4717901 C allele.
      Title: Association of GTF2I and GTF2IRD1 polymorphisms with systemic lupus erythematosus in a Chinese Han population.
    6. GTF2IRD1 binding partners are mostly involved in chromatin modification and transcriptional regulation, whilst others indicate an unexpected role in connection with the primary cilium.
      Title: The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.
    7. GTF2IRD1 is SUMOylated by the SUMO E2 ligase UBC9 and the level of SUMOylation is enhanced by PIASxbeta.
      Title: SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation.
    8. CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome; GTF2IRD1 and GTF2I are the main genes causing the cognitive defects
      Title: The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.
    9. This study provided evidences that insufficiency of GTF2IRD1 protein contributes to abnormalities of facial development, motor function and specific behavioural disorders that accompany Williams-Beuren syndrome.
      Title: Mutation of Gtf2ird1 from the Williams-Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations.
    10. functional hemizygosity for the GTF2I and GTF2IRD1 genes is the main cause of the neurocognitive profile and some aspects of the gestalt phenotype of Williams-Beuren syndrome
      Title: Partial 7q11.23 deletions further implicate GTF2I and GTF2IRD1 as the main genes responsible for the Williams-Beuren syndrome neurocognitive profile.
    Submit: New GeneRIF Correction See all GeneRIFs (21)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated 2012-10-10)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated 2012-10-10)

    ClinGen Genome Curation Page

    EBI GWAS Catalog

    Description
    A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transition between slow and fast fiber IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    general transcription factor II-I repeat domain-containing protein 1
    Names
    USE B1-binding protein
    Williams-Beuren syndrome chromosome region 11
    binding factor for early enhancer
    general transcription factor 3
    general transcription factor III
    muscle TFII-I repeat domain-containing protein 1 alpha 1
    slow-muscle-fiber enhancer-binding protein
    williams-Beuren syndrome chromosomal region 12 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_027954.2 RefSeqGene

      Range
      5002..153701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001199207.2 → NP_001186136.1  general transcription factor II-I repeat domain-containing protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001186136.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AF151354, AY648295
      Consensus CDS
      CCDS56492.1
      UniProtKB/TrEMBL
      Q59FS0
      Related
      ENSP00000397566.2, ENST00000455841.6
      Conserved Domains (1) summary
      pfam02946
      Location:597 → 669
      GTF2I; GTF2I-like repeat

    2. NM_001410888.1 → NP_001397817.1  general transcription factor II-I repeat domain-containing protein 1 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC004851, AC005015, AC211433
      Consensus CDS
      CCDS94121.1
      UniProtKB/TrEMBL
      E9PFE2
      Related
      ENSP00000418383.1, ENST00000476977.5

    3. NM_005685.4 → NP_005676.3  general transcription factor II-I repeat domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_005676.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 3. The encoded isoform (2) is shorter compared to isoform 3.
      Source sequence(s)
      AF118270, AF151354, AF156489, AY648295
      Consensus CDS
      CCDS47613.1
      UniProtKB/TrEMBL
      Q59FS0
      Related
      ENSP00000408477.2, ENST00000424337.7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    4. NM_016328.3 → NP_057412.1  general transcription factor II-I repeat domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_057412.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) uses alternate splice sites in the coding region, compared to variant 3. The encoded isoform (1) is shorter compared to isoform 3.
      Source sequence(s)
      AF151354, AY648295, BC018136
      Consensus CDS
      CCDS5571.1
      UniProtKB/Swiss-Prot
      O95444, Q6DSU6, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UHL9, Q9UI91
      UniProtKB/TrEMBL
      Q59FS0
      Related
      ENSP00000265755.3, ENST00000265755.7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      74453906..74602605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047421058.1 → XP_047277014.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

    2. XM_047421064.1 → XP_047277020.1  general transcription factor II-I repeat domain-containing protein 1 isoform X8

    3. XM_011516713.2 → XP_011515015.1  general transcription factor II-I repeat domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      Q59FS0
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    4. XM_047421056.1 → XP_047277012.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    5. XM_047421057.1 → XP_047277013.1  general transcription factor II-I repeat domain-containing protein 1 isoform X2

    6. XM_047421061.1 → XP_047277017.1  general transcription factor II-I repeat domain-containing protein 1 isoform X5

    7. XM_017012802.2 → XP_016868291.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      Q59FS0
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    8. XM_006716182.4 → XP_006716245.1  general transcription factor II-I repeat domain-containing protein 1 isoform X6

      See identical proteins and their annotated locations for XP_006716245.1

      UniProtKB/TrEMBL
      E9PFE2, Q59FS0
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    9. XM_017012805.2 → XP_016868294.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      Q59FS0

    10. XM_047421059.1 → XP_047277015.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

    11. XM_047421062.1 → XP_047277018.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

      UniProtKB/Swiss-Prot
      O95444, Q6DSU6, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UHL9, Q9UI91

    12. XM_017012804.2 → XP_016868293.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      Q59FS0
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    13. XM_047421060.1 → XP_047277016.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

    14. XM_047421066.1 → XP_047277022.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

    15. XM_047421063.1 → XP_047277019.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

      UniProtKB/Swiss-Prot
      O95444, Q6DSU6, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UHL9, Q9UI91

    16. XM_047421065.1 → XP_047277021.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      75656184..75805371
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054359379.1 → XP_054215354.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

    2. XM_054359385.1 → XP_054215360.1  general transcription factor II-I repeat domain-containing protein 1 isoform X5

    3. XM_054359380.1 → XP_054215355.1  general transcription factor II-I repeat domain-containing protein 1 isoform X2

    4. XM_054359392.1 → XP_054215367.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

    5. XM_054359383.1 → XP_054215358.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

    6. XM_054359386.1 → XP_054215361.1  general transcription factor II-I repeat domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      E9PFE2

    7. XM_054359381.1 → XP_054215356.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

    8. XM_054359389.1 → XP_054215364.1  general transcription factor II-I repeat domain-containing protein 1 isoform X8

    9. XM_054359394.1 → XP_054215369.1  general transcription factor II-I repeat domain-containing protein 1 isoform X11

    10. XM_054359390.1 → XP_054215365.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

    11. XM_054359387.1 → XP_054215362.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

      UniProtKB/Swiss-Prot
      O95444, Q6DSU6, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UHL9, Q9UI91

    12. XM_054359393.1 → XP_054215368.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

    13. XM_054359384.1 → XP_054215359.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

    14. XM_054359382.1 → XP_054215357.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

    15. XM_054359388.1 → XP_054215363.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

      UniProtKB/Swiss-Prot
      O95444, Q6DSU6, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UHL9, Q9UI91

    16. XM_054359391.1 → XP_054215366.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UHL9.1 GenPept UniProtKB/Swiss-Prot:Q9UHL9

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