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    LAMA3 laminin subunit alpha 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701313, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LAMA3provided by VGNC
    Official Full Name
    laminin subunit alpha 3provided by VGNC
    Primary source
    VGNC:VGNC:74226
    See related
    Ensembl:ENSMMUG00000004321
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LAMA3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    76
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (58451919..58724159, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (12174180..12445803)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene U5 spliceosomal RNA Neighboring gene uncharacterized LOC106994447 Neighboring gene tetratricopeptide repeat domain 39C Neighboring gene uncharacterized LOC114673734 Neighboring gene 60S ribosomal protein L23a pseudogene Neighboring gene 40S ribosomal protein S10 pseudogene Neighboring gene ankyrin repeat domain 29

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit alpha-3
    Names
    laminin, alpha 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      58451919..58724159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015121683.2 → XP_014977169.2  laminin subunit alpha-3 isoform X3

      UniProtKB/TrEMBL
      G7NKH4
      Conserved Domains (10) summary
      smart00136
      Location:46 → 297
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:610 → 660
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00282
      Location:2417 → 2552
      LamG; Laminin G domain
      cd00055
      Location:514 → 556
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3140 → 3291
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1960 → 2284
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2270 → 2398
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1829 → 2086
      Laminin_I; Laminin Domain I
      pfam00052
      Location:1500 → 1634
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1248 → 1296
      Laminin_EGF; Laminin EGF domain

    2. XM_015121682.2 → XP_014977168.2  laminin subunit alpha-3 isoform X2

      UniProtKB/TrEMBL
      F7CEZ9, G7NKH4
      Related
      ENSMMUP00000041299.3, ENSMMUT00000048263.3
      Conserved Domains (10) summary
      smart00136
      Location:46 → 297
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:631 → 681
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00282
      Location:2435 → 2570
      LamG; Laminin G domain
      cd00055
      Location:535 → 577
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3158 → 3309
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1978 → 2302
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2288 → 2416
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1847 → 2104
      Laminin_I; Laminin Domain I
      pfam00052
      Location:1518 → 1652
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1266 → 1314
      Laminin_EGF; Laminin EGF domain

    3. XM_015121681.2 → XP_014977167.2  laminin subunit alpha-3 isoform X1

      UniProtKB/TrEMBL
      G7NKH4
      Conserved Domains (10) summary
      smart00136
      Location:46 → 297
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:631 → 681
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00282
      Location:2438 → 2573
      LamG; Laminin G domain
      cd00055
      Location:535 → 577
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3161 → 3312
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1981 → 2305
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2291 → 2419
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1850 → 2107
      Laminin_I; Laminin Domain I
      pfam00052
      Location:1521 → 1655
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1269 → 1317
      Laminin_EGF; Laminin EGF domain

    4. XM_015121685.2 → XP_014977171.2  laminin subunit alpha-3 isoform X4

      UniProtKB/TrEMBL
      F6ZDD6
      Related
      ENSMMUP00000005793.3, ENSMMUT00000006152.4
      Conserved Domains (6) summary
      smart00282
      Location:826 → 961
      LamG; Laminin G domain
      COG1196
      Location:413 → 751
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:77 → 123
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1549 → 1700
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06009
      Location:679 → 807
      Laminin_II; Laminin Domain II
      pfam06008
      Location:238 → 495
      Laminin_I; Laminin Domain I
    Nucleotide Protein
    Heading Accession and Version

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