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    CD2BP2 CD2 cytoplasmic tail binding protein 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 489937, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CD2BP2provided by VGNC
    Official Full Name
    CD2 cytoplasmic tail binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:38946
    See related
    Ensembl:ENSCAFG00845014325
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CD2BP2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (17870689..17873654)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (19313603..19316566)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (17901772..17904738)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (17670660..17673625)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (17586077..17589033)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene myosin light chain 11 Neighboring gene TBC1 domain family member 10B Neighboring gene sesquipedalian-1-like Neighboring gene sialophorin Neighboring gene 40S ribosomal protein S27-like Neighboring gene quinolinate phosphoribosyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U5 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CD2 antigen cytoplasmic tail-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      17870689..17873654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038668634.1 → XP_038524562.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_038668632.1 → XP_038524560.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0M3A3
      Conserved Domains (1) summary
      cd00072
      Location:281 → 341
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    3. XM_038668633.1 → XP_038524561.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_038668631.1 → XP_038524559.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_038668629.1 → XP_038524557.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Related
      ENSCAFP00845020184.1, ENSCAFT00845025621.1
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    6. XM_038668630.1 → XP_038524558.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      17670660..17673625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038478581.1 → XP_038334509.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_038478579.1 → XP_038334507.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X2

      Conserved Domains (1) summary
      cd00072
      Location:281 → 341
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    3. XM_038478580.1 → XP_038334508.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_038478578.1 → XP_038334506.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_038478576.1 → XP_038334504.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    6. XM_038478577.1 → XP_038334505.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      17586077..17589033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038603907.1 → XP_038459835.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

    2. XM_038603905.1 → XP_038459833.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X2

    3. XM_038603906.1 → XP_038459834.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

    4. XM_038603904.1 → XP_038459832.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

    5. XM_038603902.1 → XP_038459830.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

    6. XM_038603903.1 → XP_038459831.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      17901772..17904738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038539829.1 → XP_038395757.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_038539827.1 → XP_038395755.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0M3A3
      Conserved Domains (1) summary
      cd00072
      Location:281 → 341
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    3. XM_038539828.1 → XP_038395756.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_038539826.1 → XP_038395754.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_038539824.1 → XP_038395752.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    6. XM_038539825.1 → XP_038395753.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      19313603..19316566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038542872.1 → XP_038398800.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_022419861.2 → XP_022275569.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0M3A3
      Conserved Domains (1) summary
      cd00072
      Location:281 → 341
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    3. XM_038542869.1 → XP_038398797.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd00072
      Location:248 → 308
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_005621332.4 → XP_005621389.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005621389.1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_547057.7 → XP_547057.2  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_547057.2

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    6. XM_022419860.2 → XP_022275568.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KZE2, A0A8C0M3A3, A0A8C0SM53, A0A8I3NT40
      Conserved Domains (1) summary
      cd00072
      Location:283 → 343
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.
    Nucleotide Protein
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