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    DNMT1 DNA methyltransferase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 476715, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DNMT1provided by VGNC
    Official Full Name
    DNA methyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:108242
    See related
    Ensembl:ENSCAFG00845018246
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DNMT1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (51393895..51450128)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (50741748..50797884)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (51269676..51325956)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (50599735..50657798)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (51028945..51085072)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L4 Neighboring gene sphingosine-1-phosphate receptor 2 Neighboring gene small nucleolar RNA U105B Neighboring gene eukaryotic translation initiation factor 3 subunit G Neighboring gene purinergic receptor P2Y11 Neighboring gene peter pan homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DNMT1: an emerging target in the treatment of invasive urinary bladder cancer. Dhawan D, et al. Urol Oncol, 2013 Nov. PMID 22609058
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA (cytosine-5-)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA (cytosine-5)-methyltransferase 1
    XP_022262774.1
    XP_022262775.1
    XP_022262776.1
    XP_038284600.1
    XP_038284601.1
    XP_038284602.1
    XP_038284603.1
    XP_038311338.1
    XP_038360243.1
    XP_038360244.1
    XP_038360245.1
    XP_038360246.1
    XP_038360247.1
    XP_038423275.1
    XP_038423276.1
    XP_038423277.1
    XP_038423278.1
    XP_038487423.1
    XP_038487424.1
    XP_038487425.1
    XP_038487426.1
    XP_038487427.1
    XP_533919.5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      51393895..51450128
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038428674.1 → XP_038284602.1  DNA (cytosine-5)-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (6) summary
      COG0270
      Location:1110 → 1568
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:937 → 1073
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:726 → 849
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:617 → 663
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:3 → 81
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:373 → 506
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    2. XM_038428672.1 → XP_038284600.1  DNA (cytosine-5)-methyltransferase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RQ92, A0A8I3NUZ2, A0A8P0SM11
      Related
      ENSCAFP00845025238.1, ENSCAFT00845032287.1
      Conserved Domains (6) summary
      COG0270
      Location:1135 → 1593
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:962 → 1098
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:751 → 874
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:642 → 688
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:398 → 531
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    3. XM_038428673.1 → XP_038284601.1  DNA (cytosine-5)-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (6) summary
      COG0270
      Location:1127 → 1585
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:954 → 1090
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:743 → 866
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:634 → 680
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:20 → 98
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:390 → 523
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    4. XM_038428675.1 → XP_038284603.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (5) summary
      COG0270
      Location:905 → 1363
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:732 → 868
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:521 → 644
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:412 → 458
      zf-CXXC; CXXC zinc finger domain
      pfam12047
      Location:168 → 301
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      50599735..50657798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038504318.1 → XP_038360246.1  DNA (cytosine-5)-methyltransferase 1 isoform X7

    2. XM_038504315.1 → XP_038360243.1  DNA (cytosine-5)-methyltransferase 1 isoform X5

    3. XM_038504316.1 → XP_038360244.1  DNA (cytosine-5)-methyltransferase 1 isoform X3

      Conserved Domains (6) summary
      COG0270
      Location:1135 → 1593
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:962 → 1098
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:751 → 874
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:642 → 688
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:398 → 531
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    4. XM_038504317.1 → XP_038360245.1  DNA (cytosine-5)-methyltransferase 1 isoform X6

    5. XM_038504319.1 → XP_038360247.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

      Conserved Domains (5) summary
      COG0270
      Location:905 → 1363
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:732 → 868
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:521 → 644
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:412 → 458
      zf-CXXC; CXXC zinc finger domain
      pfam12047
      Location:168 → 301
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      51028945..51085072
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038631498.1 → XP_038487426.1  DNA (cytosine-5)-methyltransferase 1 isoform X10

    2. XM_038631495.1 → XP_038487423.1  DNA (cytosine-5)-methyltransferase 1 isoform X8

    3. XM_038631496.1 → XP_038487424.1  DNA (cytosine-5)-methyltransferase 1 isoform X3

      Conserved Domains (6) summary
      COG0270
      Location:1135 → 1593
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:962 → 1098
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:751 → 874
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:642 → 688
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:398 → 531
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    4. XM_038631497.1 → XP_038487425.1  DNA (cytosine-5)-methyltransferase 1 isoform X9

    5. XM_038631499.1 → XP_038487427.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

      Conserved Domains (5) summary
      COG0270
      Location:905 → 1363
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:732 → 868
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:521 → 644
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:412 → 458
      zf-CXXC; CXXC zinc finger domain
      pfam12047
      Location:168 → 301
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      51269676..51325956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038567349.1 → XP_038423277.1  DNA (cytosine-5)-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (6) summary
      COG0270
      Location:1110 → 1568
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:937 → 1073
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:726 → 849
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:617 → 663
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:3 → 81
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:373 → 506
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    2. XM_038567347.1 → XP_038423275.1  DNA (cytosine-5)-methyltransferase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RQ92, A0A8I3NUZ2, A0A8P0SM11
      Conserved Domains (6) summary
      COG0270
      Location:1135 → 1593
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:962 → 1098
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:751 → 874
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:642 → 688
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:398 → 531
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    3. XM_038567348.1 → XP_038423276.1  DNA (cytosine-5)-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (6) summary
      COG0270
      Location:1127 → 1585
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:954 → 1090
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:743 → 866
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:634 → 680
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:20 → 98
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:390 → 523
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    4. XM_038567350.1 → XP_038423278.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (5) summary
      COG0270
      Location:905 → 1363
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:732 → 868
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:521 → 644
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:412 → 458
      zf-CXXC; CXXC zinc finger domain
      pfam12047
      Location:168 → 301
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      50741748..50797884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022407068.2 → XP_022262776.1  DNA (cytosine-5)-methyltransferase 1 isoform X13

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (7) summary
      COG0270
      Location:1117 → 1575
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:944 → 1080
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:733 → 856
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:624 → 670
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:3 → 81
      DMAP_binding; DMAP1-binding Domain
      pfam10243
      Location:151 → 338
      MIP-T3; Microtubule-binding protein MIP-T3
      pfam12047
      Location:382 → 512
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    2. XM_022407066.2 → XP_022262774.1  DNA (cytosine-5)-methyltransferase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (7) summary
      COG0270
      Location:1142 → 1600
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:969 → 1105
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:758 → 881
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:649 → 695
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam10243
      Location:176 → 363
      MIP-T3; Microtubule-binding protein MIP-T3
      pfam12047
      Location:407 → 537
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    3. XM_533919.7 → XP_533919.5  DNA (cytosine-5)-methyltransferase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RQ92, A0A8I3NUZ2, A0A8P0SM11
      Conserved Domains (6) summary
      COG0270
      Location:1135 → 1593
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:962 → 1098
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:751 → 874
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:642 → 688
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:17 → 106
      DMAP_binding; DMAP1-binding Domain
      pfam12047
      Location:398 → 531
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    4. XM_022407067.2 → XP_022262775.1  DNA (cytosine-5)-methyltransferase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (7) summary
      COG0270
      Location:1134 → 1592
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:961 → 1097
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:750 → 873
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:641 → 687
      zf-CXXC; CXXC zinc finger domain
      pfam06464
      Location:20 → 98
      DMAP_binding; DMAP1-binding Domain
      pfam10243
      Location:168 → 355
      MIP-T3; Microtubule-binding protein MIP-T3
      pfam12047
      Location:399 → 529
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

    5. XM_038455410.1 → XP_038311338.1  DNA (cytosine-5)-methyltransferase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0RQ92
      Conserved Domains (5) summary
      COG0270
      Location:905 → 1363
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04711
      Location:732 → 868
      BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      cd04760
      Location:521 → 644
      BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
      pfam02008
      Location:412 → 458
      zf-CXXC; CXXC zinc finger domain
      pfam12047
      Location:168 → 301
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain
    Nucleotide Protein
    Heading Accession and Version

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