U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    lama3 laminin subunit alpha 3 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100496680, updated on 4-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    lama3provided by Xenbase
    Official Full Name
    laminin subunit alpha 3provided by Xenbase
    Primary source
    Xenbase:XB-GENE-984634
    See related
    Ensembl:ENSXETG00000015102 AllianceGenome:Xenbase:XB-GENE-984634
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to act upstream of or within several processes, including cell adhesion; regulation of cell migration; and regulation of embryonic development. Predicted to be located in basement membrane; extracellular region; and membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See lama3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    77
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (109192494..109329919)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (94129778..94271939)

    Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100494805 Neighboring gene ankyrin repeat domain 29 Neighboring gene tetratricopeptide repeat domain 39C Neighboring gene oxysterol binding protein like 1A Neighboring gene impact RWD domain protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    laminin subunit alpha-3
    Names
    laminin, alpha 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      109192494..109329919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031903840.1 → XP_031759700.1  laminin subunit alpha-3

      UniProtKB/TrEMBL
      A0A6I8SMM3
      Related
      ENSXETP00000099495.2, ENSXETT00000100177.2
      Conserved Domains (9) summary
      smart00282
      Location:3303 → 3432
      LamG; Laminin G domain
      cd00055
      Location:1382 → 1424
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3106 → 3256
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:2091 → 2419
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06008
      Location:1968 → 2222
      Laminin_I; Laminin Domain I
      pfam06009
      Location:2400 → 2532
      Laminin_II; Laminin Domain II
      pfam00052
      Location:1634 → 1770
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1522 → 1570
      Laminin_EGF; Laminin EGF domain
      pfam00055
      Location:54 → 309
      Laminin_N; Laminin N-terminal (Domain VI)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.