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    cph2 Clr6 histone deacetylase-associated PHD protein-2 Cph2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541422, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cph2
    Official Full Name
    Clr6 histone deacetylase-associated PHD protein-2 Cph2
    Primary source
    PomBase:SPAC2F7.07c
    Locus tag
    SPOM_SPAC2F7.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rco1
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    Genomic context

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    See cph2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (544127..546259, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit Med1 Neighboring gene ncRNA Neighboring gene translation initiation factor Tif5 Neighboring gene DNA polymerase X family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SWI/SNF complex subunit Snf5 Neighboring gene GTPase-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Class I histone deacetylase complex: Structure and functional correlates. Wang X, et al. Proc Natl Acad Sci U S A, 2023 Jul 25. PMID 37459529, Free PMC Article
    2. Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult. Tang MY, et al. Gene, 2015 May 10. PMID 25701403
    3. A genetic screen for functional partners of condensin in fission yeast. Robellet X, et al. G3 (Bethesda), 2014 Feb 19. PMID 24362309, Free PMC Article
    4. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nicolas E, et al. Nat Struct Mol Biol, 2007 May. PMID 17450151
    5. Two assembly modes for SIN3 histone deacetylase complexes. Wang C, et al. Cell Discov, 2023 Apr 19. PMID 37076472, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3S complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Rpd3S complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Clr6 histone deacetylase-associated PHD protein-2 Cph2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      544127..546259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018378.3 → NP_592978.1  Clr6 histone deacetylase-associated PHD protein-2 Cph2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592978.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09698
      Conserved Domains (2) summary
      cd15534
      Location:408 → 456
      PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
      cd15535
      Location:265 → 309
      PHD1_Rco1; PHD finger 1 found in Saccharomyces cerevisiae transcriptional regulatory protein Rco1 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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