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    Spata6l spermatogenesis associated 6 like [ Mus musculus (house mouse) ]

    Gene ID: 381218, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Spata6lprovided by MGI
    Official Full Name
    spermatogenesis associated 6 likeprovided by MGI
    Primary source
    MGI:MGI:1918036
    See related
    Ensembl:ENSMUSG00000064202 AllianceGenome:MGI:1918036
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4430402I18Rik
    Summary
    Predicted to enable myosin light chain binding activity. Predicted to be involved in spermatogenesis. Predicted to be located in sperm head-tail coupling apparatus. Orthologous to human SPATA6L (spermatogenesis associated 6 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 26.8), duodenum adult (RPKM 4.7) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Spata6l in Genome Data Viewer
    Location:
    19 C1; 19 23.57 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (28899836..28945289, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (28917638..28967832, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52404 Neighboring gene solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene phospholipid phosphatase 6 Neighboring gene phytanoyl-CoA hydroxylase pseudogene Neighboring gene tektin 5 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables myosin light chain binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in sperm head-tail coupling apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis associated 6-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374140.1 → NP_001361069.1  spermatogenesis associated 6-like protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC113961
      UniProtKB/TrEMBL
      B7ZWC9, F6TAK0, F6UU42
      Conserved Domains (1) summary
      pfam14909
      Location:7 → 145
      SPATA6; Spermatogenesis-assoc protein 6

    2. NM_001374152.1 → NP_001361081.1  spermatogenesis associated 6-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC113961
      UniProtKB/Swiss-Prot
      B2RV46
      UniProtKB/TrEMBL
      B7ZWC9, F6TAK0
      Conserved Domains (2) summary
      pfam14909
      Location:1 → 91
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:127 → 334
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    3. NM_001374153.1 → NP_001361082.1  spermatogenesis associated 6-like protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC113961
      UniProtKB/TrEMBL
      B7ZWC9, F6TAK0
      Conserved Domains (2) summary
      pfam14909
      Location:7 → 131
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:167 → 374
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    4. NM_001374154.1 → NP_001361083.1  spermatogenesis associated 6-like protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC113961
      UniProtKB/TrEMBL
      B7ZWC9, B7ZWD0, F6TAK0
      Related
      ENSMUSP00000132800.2, ENSMUST00000164777.8
      Conserved Domains (2) summary
      pfam14909
      Location:1 → 77
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:113 → 320
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    5. NM_198651.2 → NP_941053.2  spermatogenesis associated 6-like protein isoform 2

      See identical proteins and their annotated locations for NP_941053.2

      Status: VALIDATED

      Source sequence(s)
      AK014471, AK031997
      Consensus CDS
      CCDS37948.1
      UniProtKB/Swiss-Prot
      B2RV46
      UniProtKB/TrEMBL
      B7ZWC9, F6TAK0
      Related
      ENSMUSP00000025872.7, ENSMUST00000025872.13
      Conserved Domains (2) summary
      pfam14909
      Location:1 → 91
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:127 → 334
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      28899836..28945289 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161620.1 → XP_036017513.1  spermatogenesis associated 6-like protein isoform X4

      Conserved Domains (1) summary
      pfam14909
      Location:89 → 143
      SPATA6; Spermatogenesis-assoc protein 6

    2. XM_036161619.1 → XP_036017512.1  spermatogenesis associated 6-like protein isoform X3

      UniProtKB/TrEMBL
      B7ZWC9, F6TAK0, F6UU42
      Related
      ENSMUSP00000123818.2, ENSMUST00000162110.8
      Conserved Domains (1) summary
      pfam14909
      Location:7 → 145
      SPATA6; Spermatogenesis-assoc protein 6

    3. XM_011247274.4 → XP_011245576.3  spermatogenesis associated 6-like protein isoform X2

      Conserved Domains (2) summary
      pfam14909
      Location:206 → 323
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:359 → 566
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    4. XM_011247272.4 → XP_011245574.3  spermatogenesis associated 6-like protein isoform X1

      Conserved Domains (2) summary
      pfam14909
      Location:206 → 337
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:373 → 580
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    5. XM_030250980.2 → XP_030106840.1  spermatogenesis associated 6-like protein isoform X5

      UniProtKB/TrEMBL
      B7ZWC9, B7ZWD0, F6TAK0
      Conserved Domains (2) summary
      pfam14909
      Location:1 → 77
      SPATA6; Spermatogenesis-assoc protein 6
      pfam15741
      Location:113 → 320
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

    RNA

    1. XR_001782595.3 RNA Sequence

    2. XR_001782596.3 RNA Sequence

    3. XR_003952793.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2RV46.1 GenPept UniProtKB/Swiss-Prot:B2RV46

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