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    swr1 Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361561, updated on 18-Sep-2024

    Summary

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    Official Symbol
    swr1
    Official Full Name
    Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1
    Primary source
    PomBase:SPAC11E3.01c
    Locus tag
    SPOM_SPAC11E3.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mod22; SPAC2H10.03c
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    Genomic context

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    See swr1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5277395..5281407, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcription factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 26S proteasome regulatory particle assembly protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Munc family exocytic/endocytic regulator Ync13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improved tools for efficient mapping of fission yeast genes: identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1. Anders A, et al. Yeast, 2008 Dec. PMID 19160458, Free PMC Article
    2. Podbat: a novel genomic tool reveals Swr1-independent H2A.Z incorporation at gene coding sequences through epigenetic meta-analysis. Sadeghi L, et al. PLoS Comput Biol, 2011 Aug. PMID 21901086, Free PMC Article
    3. The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. Buchanan L, et al. PLoS Genet, 2009 Nov. PMID 19911051, Free PMC Article
    4. Activity of a C-terminal plant homeodomain (PHD) of Msc1 is essential for function. Qiu X, et al. J Biol Chem, 2010 Nov 19. PMID 20858896, Free PMC Article
    5. Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast. Hou H, et al. J Biol Chem, 2010 Jan 15. PMID 19910462, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mod22-1, a modifier of microtubule nucleation phenotypes, encodes a truncation allele of Swr1, a chromatin-remodelling factor involved in nucleosomal deposition of H2A.Z histone variant Pht1.
      Title: Improved tools for efficient mapping of fission yeast genes: identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP-dependent H2AZ histone chaperone activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables DNA binding IC
    Inferred by Curator
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5277395..5281407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356200.2 → NP_001342781.1  Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13682, Q9URL5
      Conserved Domains (3) summary
      pfam00176
      Location:450 → 745
      SNF2_N; SNF2 family N-terminal domain
      pfam07529
      Location:116 → 177
      HSA; HSA
      cl26465
      Location:991 → 1145
      SNF2_N; SNF2 family N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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