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    LAMA1 laminin subunit alpha 1 [ Hyaena hyaena (striped hyena) ]

    Gene ID: 120221358, updated on 21-Mar-2024

    Summary

    Gene symbol
    LAMA1
    Gene description
    laminin subunit alpha 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Hyaena hyaena
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae; Hyaena
    Orthologs
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    Genomic context

    See LAMA1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    63
    Annotation release Status Assembly Chr Location
    100 current ASM300989v1 (GCF_003009895.1) Unplaced Scaffold NW_024081407.1 (649566..816876, complement)

    NW_024081407.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 28 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene uncharacterized LOC120221365 Neighboring gene uncharacterized LOC120221359 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC120221366 Neighboring gene leucine rich repeat containing 30

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NW_024081407 Unplaced Scaffold Reference ASM300989v1 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in blood vessel morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in camera-type eye development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Hyaena hyaena Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM300989v1 Primary Assembly

    Genomic

    1. NW_024081407.1 Reference ASM300989v1 Primary Assembly

      Range
      649566..816876 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039218722.1XP_039074653.1  laminin subunit alpha-1 isoform X2

      Conserved Domains (9) summary
      smart00136
      Location:20272
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:9561000
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:746794
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:23122468
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06008
      Location:15801836
      Laminin_I; Laminin Domain I
      pfam06009
      Location:20172150
      Laminin_II; Laminin Domain II
      pfam00052
      Location:572712
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:907953
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:27532882
      Laminin_G_1; Laminin G domain
    2. XM_039218721.1XP_039074652.1  laminin subunit alpha-1 isoform X1

      Conserved Domains (10) summary
      PRK15041
      Location:18142121
      PRK15041; methyl-accepting chemotaxis protein
      smart00136
      Location:20272
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:9561000
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:746794
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:23132469
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06008
      Location:15801836
      Laminin_I; Laminin Domain I
      pfam06009
      Location:20182151
      Laminin_II; Laminin Domain II
      pfam00052
      Location:572712
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:907953
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:27542883
      Laminin_G_1; Laminin G domain