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    MYO5A myosin VA [ Trichechus manatus latirostris (Florida manatee) ]

    Gene ID: 101352971, updated on 8-Mar-2024

    Summary

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    Gene symbol
    MYO5A
    Gene description
    myosin VA
    See related
    EnsemblRapid:ENSTMLG00000015169
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trichechus manatus latirostris (sub-species: latirostris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
    Orthologs
    human mouse all
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    Genomic context

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    See MYO5A in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004443988.1 (14912234..15184874, complement)

    NW_004443988.1Genomic Context describing neighboring genes Neighboring gene G protein subunit beta 5 Neighboring gene myosin VC Neighboring gene lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial pseudogene Neighboring gene cAMP regulated phosphoprotein 19 Neighboring gene atos homolog A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004443988 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microfilament motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle transport along actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    unconventional myosin-Va

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference TriManLat1.0 Primary Assembly

    Genomic

    1. NW_004443988.1 Reference TriManLat1.0 Primary Assembly

      Range
      14912234..15184874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023732489.1 → XP_023588257.1  unconventional myosin-Va isoform X4

      UniProtKB/TrEMBL
      A0A2Y9R1H1
      Conserved Domains (3) summary
      cd01380
      Location:83 → 703
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1455 → 1829
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl27381
      Location:7 → 1397
      Myosin_head; Myosin head (motor domain)

    2. XM_023732490.1 → XP_023588258.1  unconventional myosin-Va isoform X5

      UniProtKB/TrEMBL
      A0A2Y9R9H8
      Conserved Domains (4) summary
      smart00015
      Location:765 → 786
      IQ; Calmodulin-binding motif
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1451 → 1825
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl25732
      Location:902 → 1414
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_023732488.1 → XP_023588256.1  unconventional myosin-Va isoform X3

      UniProtKB/TrEMBL
      A0A2Y9R474
      Conserved Domains (4) summary
      smart00015
      Location:765 → 786
      IQ; Calmodulin-binding motif
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1476 → 1850
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl25732
      Location:895 → 1439
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_023732487.1 → XP_023588255.1  unconventional myosin-Va isoform X1

      UniProtKB/TrEMBL
      A0A2Y9QY18
      Conserved Domains (3) summary
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1503 → 1877
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl27381
      Location:7 → 1445
      Myosin_head; Myosin head (motor domain)

    5. XM_023732494.1 → XP_023588262.1  unconventional myosin-Va isoform X8

      UniProtKB/TrEMBL
      A0A2Y9R1H6
      Conserved Domains (3) summary
      cl03379
      Location:1228 → 1602
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl22853
      Location:2 → 476
      Motor_domain; Myosin and Kinesin motor domain
      cl27381
      Location:1 → 1170
      Myosin_head; Myosin head (motor domain)

    6. XM_023732497.1 → XP_023588265.1  unconventional myosin-Va isoform X9

      UniProtKB/TrEMBL
      A0A2Y9R8W5
      Conserved Domains (3) summary
      cl03379
      Location:1181 → 1555
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl22853
      Location:1 → 429
      Motor_domain; Myosin and Kinesin motor domain
      cl27381
      Location:2 → 1123
      Myosin_head; Myosin head (motor domain)

    7. XM_023732496.1 → XP_023588264.1  unconventional myosin-Va isoform X9

      UniProtKB/TrEMBL
      A0A2Y9R8W5
      Conserved Domains (3) summary
      cl03379
      Location:1181 → 1555
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl22853
      Location:1 → 429
      Motor_domain; Myosin and Kinesin motor domain
      cl27381
      Location:2 → 1123
      Myosin_head; Myosin head (motor domain)

    8. XM_023732495.1 → XP_023588263.1  unconventional myosin-Va isoform X9

      UniProtKB/TrEMBL
      A0A2Y9R8W5
      Conserved Domains (3) summary
      cl03379
      Location:1181 → 1555
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl22853
      Location:1 → 429
      Motor_domain; Myosin and Kinesin motor domain
      cl27381
      Location:2 → 1123
      Myosin_head; Myosin head (motor domain)

    9. XM_004377676.2 → XP_004377733.2  unconventional myosin-Va isoform X2

      UniProtKB/TrEMBL
      A0A2Y9DP93
      Related
      ENSTMLP00000022676.1, ENSTMLT00000024309.1
      Conserved Domains (5) summary
      smart00015
      Location:765 → 786
      IQ; Calmodulin-binding motif
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      pfam00612
      Location:838 → 858
      IQ; IQ calmodulin-binding motif
      cl03379
      Location:1478 → 1852
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl25732
      Location:927 → 1431
      SMC_N; RecF/RecN/SMC N terminal domain

    10. XM_023732491.1 → XP_023588259.1  unconventional myosin-Va isoform X6

      UniProtKB/TrEMBL
      A0A2Y9R8W0
      Conserved Domains (3) summary
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1503 → 1647
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl27381
      Location:7 → 1445
      Myosin_head; Myosin head (motor domain)

    11. XM_023732493.1 → XP_023588261.1  unconventional myosin-Va isoform X7

      UniProtKB/TrEMBL
      A0A2Y9R479
      Conserved Domains (3) summary
      cd01380
      Location:83 → 751
      MYSc_Myo5; class V myosin, motor domain
      cl03379
      Location:1503 → 1597
      Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
      cl27381
      Location:7 → 1445
      Myosin_head; Myosin head (motor domain)
    Nucleotide Protein
    Heading Accession and Version

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