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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_000857.5 → NP_000848.1 guanylate cyclase soluble subunit beta-1 isoform 2
See identical proteins and their annotated locations for NP_000848.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1.
- Source sequence(s)
-
AC114761, AI189698, BC026332, DB536632, DC342619, X66533
- Consensus CDS
-
CCDS47154.1
- UniProtKB/Swiss-Prot
- B7Z426, Q02153, Q86WY5
- UniProtKB/TrEMBL
-
B2RCP1
- Related
- ENSP00000264424.8, ENST00000264424.13
- Conserved Domains (3) summary
-
- pfam00211
Location:412 → 605
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:2 → 166
- HNOB; Haem-NO-binding
- pfam07701
Location:207 → 406
- HNOBA; Heme NO binding associated
-
NM_001291951.3 → NP_001278880.1 guanylate cyclase soluble subunit beta-1 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC114761, AI189698, AK300296, AK315944, BC026332, DB536632
- Consensus CDS
-
CCDS77975.1
- UniProtKB/TrEMBL
- B7Z6G8, E9PCN2
- Related
- ENSP00000426786.1, ENST00000502959.5
- Conserved Domains (4) summary
-
- smart00044
Location:407 → 606
- CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
- pfam00211
Location:434 → 627
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:2 → 188
- HNOB; Haem-NO-binding
- pfam07701
Location:229 → 428
- HNOBA; Heme NO binding associated
-
NM_001291952.3 → NP_001278881.1 guanylate cyclase soluble subunit beta-1 isoform 3
See identical proteins and their annotated locations for NP_001278881.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, initiates translation at an alternate start codon and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 3, which is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC114761, AI189698, AK296680, BC026332, DB536632, DC342619
- Consensus CDS
-
CCDS77977.1
- UniProtKB/TrEMBL
-
B2RCP1
- Related
- ENSP00000426319.1, ENST00000505764.5
- Conserved Domains (3) summary
-
- pfam00211
Location:392 → 585
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:6 → 146
- HNOB; Haem-NO-binding
- pfam07701
Location:187 → 386
- HNOBA; Heme NO binding associated
-
NM_001291953.3 → NP_001278882.1 guanylate cyclase soluble subunit beta-1 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, initiates translation at a downstream start codon and contains multiple coding region differences, compared to variant 1. It encodes isoform 4, which is shorter than isoform 1.
- Source sequence(s)
-
AC114761, AF020340, AI189698, AK307838, BC026332, DB536632, DC317249, DC342619
- Consensus CDS
-
CCDS75203.1
- UniProtKB/TrEMBL
- B7Z9H9, D6RC99
- Related
- ENSP00000422313.1, ENST00000507146.5
- Conserved Domains (3) summary
-
- pfam00211
Location:387 → 580
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:1 → 98
- HNOB; Haem-NO-binding
- pfam07701
Location:139 → 381
- HNOBA; Heme NO binding associated
-
NM_001291954.3 → NP_001278883.1 guanylate cyclase soluble subunit beta-1 isoform 5
See identical proteins and their annotated locations for NP_001278883.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) lacks an alternate in-frame exon in the 5' coding region and contains an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 5, which is shorter than isoform 1.
- Source sequence(s)
-
AC114761, AF020340, AI189698, BC026332, DB536632, DC342619
- Consensus CDS
-
CCDS77976.1
- UniProtKB/TrEMBL
-
B2RCP1
- Related
- ENSP00000420842.1, ENST00000503520.5
- Conserved Domains (3) summary
-
- pfam00211
Location:392 → 572
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:2 → 166
- HNOB; Haem-NO-binding
- pfam07701
Location:207 → 392
- HNOBA; Heme NO binding associated
-
NM_001291955.3 → NP_001278884.1 guanylate cyclase soluble subunit beta-1 isoform 6
See identical proteins and their annotated locations for NP_001278884.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR and 5' coding region, initiates translation at a downstream start codon and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 6, which is shorter than isoform 1.
- Source sequence(s)
-
AC114761, AI189698, AK315944, BC026332, DB536632
- Consensus CDS
-
CCDS77978.1
- UniProtKB/TrEMBL
- B7Z685, B7Z9H9
- Related
- ENSP00000427226.1, ENST00000505154.5
- Conserved Domains (3) summary
-
- pfam00211
Location:344 → 537
- Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
- pfam07700
Location:1 → 98
- HNOB; Haem-NO-binding
- pfam07701
Location:139 → 338
- HNOBA; Heme NO binding associated