pfam07700: HNOB (this model, PSSM-Id:400167 is obsolete and has been replaced by 462233)
Haem-NO-binding
The HNOB (Haem NO Binding) domain, is a predominantly alpha-helical domain and binds heme via a covalent linkage to histidine. It is a haem protein sensor (SONO) that displays femtomolar affinity for nitrous oxide, NO. It is predicted to function as a haem-dependent sensor for gaseous ligands and to transduce diverse downstream signals in both bacteria and animals.
Jiyao W et al.(2023). "The conserved domain database in 2023.",