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    SOWAHA sosondowah ankyrin repeat domain family member A [ Homo sapiens (human) ]

    Gene ID: 134548, updated on 17-Sep-2024

    Summary

    Official Symbol
    SOWAHAprovided by HGNC
    Official Full Name
    sosondowah ankyrin repeat domain family member Aprovided by HGNC
    Primary source
    HGNC:HGNC:27033
    See related
    Ensembl:ENSG00000198944 AllianceGenome:HGNC:27033
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ANKRD43
    Orthologs
    NEW
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    Genomic context

    See SOWAHA in Genome Data Viewer
    Location:
    5q31.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (132813302..132816786)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (133333040..133336524)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (132148994..132152478)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene kinesin family member 3A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23094 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16332 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16333 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16334 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16335 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23096 Neighboring gene septin 8 Neighboring gene cyclin I family member 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16336 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16337 Neighboring gene Sharpr-MPRA regulatory region 2681 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16338 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132150138-132150638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132150639-132151139 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16339 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16340 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16341 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16342 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16343 Neighboring gene shroom family member 1 Neighboring gene U7 small nuclear RNA Neighboring gene RNA, U7 small nuclear 15 pseudogene

    Genomic regions, transcripts, and products

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of sosondowah ankyrin repeat domain family member A (SOWAHA; ANKRD43) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein SOWAHA
    Names
    ankyrin repeat domain-containing protein 43
    protein sosondowah homolog A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175873.6NP_787069.4  ankyrin repeat domain-containing protein SOWAHA precursor

      Status: VALIDATED

      Source sequence(s)
      AC004775, KC877113
      Consensus CDS
      CCDS43361.1
      UniProtKB/Swiss-Prot
      Q2M3V2, Q8NAE7
      Related
      ENSP00000367965.2, ENST00000378693.4
      Conserved Domains (3) summary
      cd00204
      Location:346438
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:346405
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:345382
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      132813302..132816786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      133333040..133336524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)