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    LGI2 leucine rich repeat LGI family member 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 488853, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LGI2provided by VGNC
    Official Full Name
    leucine rich repeat LGI family member 2provided by VGNC
    Primary source
    VGNC:VGNC:49726
    See related
    Ensembl:ENSCAFG00845007610
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (86155381..86187875)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (87694029..87726513)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (85779270..85811791)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (85288432..85320930)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (85393580..85426122)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase type 2 beta Neighboring gene Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Neighboring gene uncharacterized LOC102154940 Neighboring gene uncharacterized LOC119870877 Neighboring gene coiled-coil domain containing 149 Neighboring gene uncharacterized LOC111095318

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LGI2 truncation causes a remitting focal epilepsy in dogs. Seppälä EH, et al. PLoS Genet, 2011 Jul. PMID 21829378, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inhibitory synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat LGI family member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      86155381..86187875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038662064.1 → XP_038517992.1  leucine-rich repeat LGI family member 2

      UniProtKB/TrEMBL
      A0A8C0RAS5, A0A8P0NHY5
      Related
      ENSCAFP00845010408.1, ENSCAFT00845013415.1
      Conserved Domains (4) summary
      TIGR00864
      Location:141 → 216
      PCC; polycystin cation channel protein
      sd00031
      Location:112 → 135
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:267 → 305
      EPTP; EPTP domain
      pfam13855
      Location:111 → 170
      LRR_8; Leucine rich repeat

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      85288432..85320930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038472574.1 → XP_038328502.1  leucine-rich repeat LGI family member 2

      Conserved Domains (4) summary
      TIGR00864
      Location:141 → 216
      PCC; polycystin cation channel protein
      sd00031
      Location:112 → 135
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:267 → 305
      EPTP; EPTP domain
      pfam13855
      Location:111 → 170
      LRR_8; Leucine rich repeat

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      85393580..85426122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038597842.1 → XP_038453770.1  leucine-rich repeat LGI family member 2

      Conserved Domains (4) summary
      TIGR00864
      Location:141 → 216
      PCC; polycystin cation channel protein
      sd00031
      Location:112 → 135
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:267 → 305
      EPTP; EPTP domain
      pfam13855
      Location:111 → 170
      LRR_8; Leucine rich repeat

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      85779270..85811791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038533560.1 → XP_038389488.1  leucine-rich repeat LGI family member 2

      UniProtKB/TrEMBL
      A0A8C0LVH3, A0A8C0RAS5

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      87694029..87726513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022416405.2 → XP_022272113.2  leucine-rich repeat LGI family member 2

      UniProtKB/TrEMBL
      A0A8C0RAS5, A0A8P0NHY5
      Conserved Domains (4) summary
      TIGR00864
      Location:141 → 216
      PCC; polycystin cation channel protein
      sd00031
      Location:112 → 135
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:267 → 305
      EPTP; EPTP domain
      pfam13855
      Location:111 → 170
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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