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    1700006A11Rik RIKEN cDNA 1700006A11 gene [ Mus musculus (house mouse) ]

    Gene ID: 71824, updated on 12-May-2024

    Summary

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    Official Symbol
    1700006A11Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 1700006A11 geneprovided by MGI
    Primary source
    MGI:MGI:1919074
    See related
    Ensembl:ENSMUSG00000027973 AllianceGenome:MGI:1919074
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable GTPase activator activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 23.1) See more
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    Genomic context

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    See 1700006A11Rik in Genome Data Viewer
    Location:
    3 G1; 3 54.68 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (124194639..124219688, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (124400990..124426039, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene translocation associated membrane protein 1-like 1 Neighboring gene STARR-seq mESC enhancer starr_08919 Neighboring gene prothymosin alpha pseudogene Neighboring gene predicted gene, 22575 Neighboring gene predicted gene, 22900 Neighboring gene RIKEN cDNA 1700003H04 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Rho GTPase-activating proteins: Regulators of Rho GTPase activity in neuronal development and CNS diseases. Huang GH, et al. Mol Cell Neurosci, 2017 Apr. PMID 28163190
    2. A novel group of multi-GAP-domain proteins. Ruan Y, et al. Mol Reprod Dev, 2008 Oct. PMID 18363199, Free PMC Article
    3. Current knowledge of the large RhoGAP family of proteins. Tcherkezian J, et al. Biol Cell, 2007 Feb. PMID 17222083
    4. Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. Strong ER, et al. Genes (Basel), 2010 Dec 2. PMID 21779533, Free PMC Article
    5. Characterization of the piRNA complex from rat testes. Lau NC, et al. Science, 2006 Jul 21. PMID 16778019

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC71824

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357195.1 → NP_001344124.1  uncharacterized protein LOC71824 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK005660, AK132965
      UniProtKB/TrEMBL
      Q3V0Q9, Q9DAP3
      Conserved Domains (2) summary
      cd04402
      Location:13 → 186
      RhoGAP_ARHGAP20; RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by ...
      cl02570
      Location:293 → 468
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    2. NM_027939.2 → NP_082215.1  uncharacterized protein LOC71824 isoform 1

      See identical proteins and their annotated locations for NP_082215.1

      Status: VALIDATED

      Source sequence(s)
      AK132965, BC137977
      Consensus CDS
      CCDS51064.1
      UniProtKB/TrEMBL
      B9EHI3, Q3V0Q9
      Related
      ENSMUSP00000029598.6, ENSMUST00000029598.10
      Conserved Domains (2) summary
      cd04402
      Location:66 → 258
      RhoGAP_ARHGAP20; RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by ...
      cl02570
      Location:365 → 540
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      124194639..124219688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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