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    IDH1 isocitrate dehydrogenase (NADP(+)) 1 [ Sus scrofa (pig) ]

    Gene ID: 102166364, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IDH1provided by VGNC
    Official Full Name
    isocitrate dehydrogenase (NADP(+)) 1provided by VGNC
    Primary source
    VGNC:VGNC:111751
    See related
    Ensembl:ENSSSCG00000023264
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    IDH; IDP
    Expression
    Broad expression in subcutaneous adipose (RPKM 72.3), liver (RPKM 67.5) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See IDH1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 15 NC_010457.5 (111341153..111362330, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 15 NC_010457.4 (122861672..122883887, complement)

    Chromosome 15 - NC_010457.5Genomic Context describing neighboring genes Neighboring gene gamma-crystallin A Neighboring gene chromosome 15 C2orf80 homolog Neighboring gene uncharacterized LOC110257036 Neighboring gene phosphoinositide kinase, FYVE-type zinc finger containing Neighboring gene parathyroid hormone 2 receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables isocitrate dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isocitrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isocitrate dehydrogenase [NADP] cytoplasmic
    Names
    Cytosolic NADP-isocitrate dehydrogenase
    Isocitrate dehydrogenase [NADP] cytoplasmic
    NADP(+)-specific ICDH
    Oxalosuccinate decarboxylase
    isocitrate dehydrogenase (NADP(+)) 1, cytosolic

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010457.5 Reference Sscrofa11.1 Primary Assembly

      Range
      111341153..111362330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021074908.1 → XP_020930567.1  isocitrate dehydrogenase [NADP] cytoplasmic isoform X1

      UniProtKB/TrEMBL
      A0A8D0HUL6, A0A8D1BE35
      Conserved Domains (1) summary
      PTZ00435
      Location:39 → 449
      PTZ00435; isocitrate dehydrogenase; Provisional

    2. XM_005672137.3 → XP_005672194.1  isocitrate dehydrogenase [NADP] cytoplasmic isoform X2

      See identical proteins and their annotated locations for XP_005672194.1

      UniProtKB/TrEMBL
      A0A4X1UYV3, A0A4X1UZU9, A0A8D0HUL6
      Related
      ENSSSCP00000040163.3, ENSSSCT00000059742.3
      Conserved Domains (1) summary
      PTZ00435
      Location:1 → 411
      PTZ00435; isocitrate dehydrogenase; Provisional

    3. XM_005672136.3 → XP_005672193.1  isocitrate dehydrogenase [NADP] cytoplasmic isoform X2

      See identical proteins and their annotated locations for XP_005672193.1

      UniProtKB/TrEMBL
      A0A4X1UYV3, A0A4X1UZU9, A0A8D0HUL6
      Related
      ENSSSCP00000050907.3, ENSSSCT00000043430.3
      Conserved Domains (1) summary
      PTZ00435
      Location:1 → 411
      PTZ00435; isocitrate dehydrogenase; Provisional

    4. XM_013984433.2 → XP_013839887.1  isocitrate dehydrogenase [NADP] cytoplasmic isoform X2

      UniProtKB/TrEMBL
      A0A4X1UYV3, A0A4X1UZU9, A0A8D0HUL6
      Conserved Domains (1) summary
      PTZ00435
      Location:1 → 411
      PTZ00435; isocitrate dehydrogenase; Provisional

    5. XM_013984432.2 → XP_013839886.1  isocitrate dehydrogenase [NADP] cytoplasmic isoform X2

      UniProtKB/TrEMBL
      A0A4X1UYV3, A0A4X1UZU9, A0A8D0HUL6
      Conserved Domains (1) summary
      PTZ00435
      Location:1 → 411
      PTZ00435; isocitrate dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20304.1 GenPept UniProtKB/Swiss-Prot:P20304

    Gene LinkOut

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