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LOC588152 rho GTPase-activating protein 35 [ Strongylocentrotus purpuratus (purple sea urchin) ]

Gene ID: 588152, updated on 14-Dec-2023

Summary

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Gene symbol
LOC588152
Gene description
rho GTPase-activating protein 35
Gene type
protein coding
RefSeq status
MODEL
Organism
Strongylocentrotus purpuratus
Lineage
Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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Genomic context

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See LOC588152 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
46
Annotation release Status Assembly Chr Location
102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145606.1 (25157938..25268336, complement)
Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577742.1 (312061..362012)

NW_022145606.1Genomic Context describing neighboring genes Neighboring gene heparan sulfate glucosamine 3-O-sulfotransferase 1 Neighboring gene GTP cyclohydrolase 1-like Neighboring gene probable Werner syndrome ATP-dependent helicase homolog 1 Neighboring gene uncharacterized LOC115927319 Neighboring gene microfibrillar-associated protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 35
Names
beta-chimaerin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Spur_5.0 Primary Assembly

Genomic

  1. NW_022145606.1 Reference Spur_5.0 Primary Assembly

    Range
    25157938..25268336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030993082.1 → XP_030848942.1  rho GTPase-activating protein 35 isoform X1

    UniProtKB/TrEMBL
    A0A7M7PC37
    Conserved Domains (5) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:958 → 1382
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1760 → 1929
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam03154
    Location:1341 → 1588
    Atrophin-1; Atrophin-1 family
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  2. XM_030993089.1 → XP_030848949.1  rho GTPase-activating protein 35 isoform X8

    UniProtKB/TrEMBL
    A0A7M7T2G8
    Conserved Domains (5) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1552 → 1723
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam03154
    Location:1133 → 1380
    Atrophin-1; Atrophin-1 family
    pfam15324
    Location:864 → 1176
    TALPID3; Hedgehog signalling target
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  3. XM_030993085.1 → XP_030848945.1  rho GTPase-activating protein 35 isoform X4

    UniProtKB/TrEMBL
    A0A7M7PE07
    Conserved Domains (5) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:959 → 1288
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1666 → 1837
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam03154
    Location:1247 → 1494
    Atrophin-1; Atrophin-1 family
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  4. XM_030993096.1 → XP_030848956.1  rho GTPase-activating protein 35 isoform X14

    UniProtKB/TrEMBL
    A0A7M7PBZ1
    Conserved Domains (3) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1435 → 1606
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  5. XM_030993094.1 → XP_030848954.1  rho GTPase-activating protein 35 isoform X12

    UniProtKB/TrEMBL
    A0A7M7PC50
    Conserved Domains (3) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1460 → 1631
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  6. XM_030993090.1 → XP_030848950.1  rho GTPase-activating protein 35 isoform X9

    UniProtKB/TrEMBL
    A0A7M7PD13
    Conserved Domains (3) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1500 → 1671
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  7. XM_030993095.1 → XP_030848955.1  rho GTPase-activating protein 35 isoform X13

    UniProtKB/TrEMBL
    A0A7M7PAY1
    Conserved Domains (4) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1458 → 1629
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam03154
    Location:1082 → 1286
    Atrophin-1; Atrophin-1 family
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  8. XM_030993092.1 → XP_030848952.1  rho GTPase-activating protein 35 isoform X11

    UniProtKB/TrEMBL
    A0A7M7PDY7
    Conserved Domains (3) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1461 → 1632
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  9. XM_030993091.1 → XP_030848951.1  rho GTPase-activating protein 35 isoform X10

    UniProtKB/TrEMBL
    A0A7M7PBH4
    Conserved Domains (4) summary
    PTZ00449
    Location:1055 → 1289
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    cd00159
    Location:1483 → 1654
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  10. XM_030993083.1 → XP_030848943.1  rho GTPase-activating protein 35 isoform X2

    UniProtKB/TrEMBL
    A0A7M7PAX1
    Conserved Domains (5) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:958 → 1352
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1730 → 1901
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam03154
    Location:1311 → 1558
    Atrophin-1; Atrophin-1 family
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  11. XM_030993088.1 → XP_030848948.1  rho GTPase-activating protein 35 isoform X7

    UniProtKB/TrEMBL
    A0A7M7PBI9
    Conserved Domains (4) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:958 → 1392
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1564 → 1735
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  12. XM_030993087.1 → XP_030848947.1  rho GTPase-activating protein 35 isoform X6

    UniProtKB/TrEMBL
    A0A7M7T2F0
    Conserved Domains (4) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:958 → 1410
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1582 → 1753
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

  13. XM_030993086.1 → XP_030848946.1  rho GTPase-activating protein 35 isoform X5

    UniProtKB/TrEMBL
    A0A7M7PGG8

  14. XM_030993084.1 → XP_030848944.1  rho GTPase-activating protein 35 isoform X3

    UniProtKB/TrEMBL
    A0A7M7PBY0
    Conserved Domains (4) summary
    cd00882
    Location:25 → 237
    Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    PHA03247
    Location:958 → 1486
    PHA03247; large tegument protein UL36; Provisional
    cd00159
    Location:1675 → 1846
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16512
    Location:253 → 331
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
Nucleotide Protein
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