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isg20l2.S interferon stimulated exonuclease gene 20kDa like 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734604, updated on 4-Nov-2024

Summary

Official Symbol
isg20l2.S
Official Full Name
interferon stimulated exonuclease gene 20kDa like 2 S homeolog
Primary source
Xenbase:XB-GENE-959115
Locus tag
XELAEV_18042771mg
See related
EnsemblRapid:ENSXLAG00005022286 AllianceGenome:Xenbase:XB-GENE-959115
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
isg20l2
Summary
Predicted to enable 3'-5'-RNA exonuclease activity and nucleic acid binding activity. Predicted to be located in nucleus. Orthologous to human ISG20L2 (interferon stimulated exonuclease gene 20 like 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See isg20l2.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (97622090..97630900)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (92596217..92602280)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene ETS variant transcription factor 3 S homeolog Neighboring gene uncharacterized LOC108700360 Neighboring gene cellular retinoic acid binding protein 2 S homeolog Neighboring gene DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC115620

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
interferon stimulated exonuclease gene 20kDa like 2 S homeolog
Names
interferon stimulated exonuclease gene 20kDa-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096079.2NP_001089548.1  interferon stimulated exonuclease gene 20kDa like 2 S homeolog

    See identical proteins and their annotated locations for NP_001089548.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097861
    UniProtKB/TrEMBL
    Q4V7K3
    Related
    ENSXLAP00005065531.1, ENSXLAT00005067048.1
    Conserved Domains (2) summary
    cd06149
    Location:196352
    ISG20; DEDDh 3'-5' exonuclease domain of Interferon Stimulated Gene product of 20 kDa, and similar proteins
    COG0847
    Location:196351
    DnaQ; DNA polymerase III, epsilon subunit or related 3'-5' exonuclease [Replication, recombination and repair]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    97622090..97630900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041574324.1XP_041430258.1  interferon stimulated exonuclease gene 20kDa like 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8F4J3, A0A974C4W5
    Related
    ENSXLAP00005065565.1, ENSXLAT00005067081.1
    Conserved Domains (1) summary
    cd06149
    Location:196352
    ISG20; DEDDh 3'-5' exonuclease domain of Interferon Stimulated Gene product of 20 kDa, and similar proteins