dsc3.S desmocollin 3 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: dsc3.S
Official Full Name: desmocollin 3 S homeolog
Primary source: Xenbase:XB-GENE-976997
Locus tag: XELAEV_18033676mg
See related: EnsemblRapid:ENSXLAG00005032091 AllianceGenome:Xenbase:XB-GENE-976997
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: dsc3
Summary: Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to act upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to be located in adherens junction; desmosome; and plasma membrane. Predicted to be part of catenin complex. Orthologous to human DSC3 (desmocollin 3). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 6S

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6S	NC_054382.1 (97149461..97184184, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6S	NC_030735.1 (88472265..88507075, complement)

Chromosome 6S - NC_054382.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cadherin binding	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within adherens junction organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell-cell adhesion mediated by cadherin	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell-cell junction assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sprouting angiogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in adherens junction	IEA Inferred from Electronic Annotation more info
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
part_of catenin complex	IEA Inferred from Electronic Annotation more info
located_in desmosome	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: desmocollin 3 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095736.1 → NP_001089205.1 desmocollin 3 S homeolog precursor

See identical proteins and their annotated locations for NP_001089205.1

Status: PROVISIONAL

Source sequence(s)

BC089120

UniProtKB/TrEMBL

A0A974HE68, Q5HZ99

Related

ENSXLAP00005096249.1, ENSXLAT00005098020.1

Conserved Domains (4) summary

cd11304
Location:247 → 348

Cadherin_repeat; Cadherin tandem repeat domain

smart00112
Location:158 → 238

CA; Cadherin repeats

smart01055
Location:29 → 109

Cadherin_pro; Cadherin prodomain like

pfam01049
Location:792 → 898

Cadherin_C; Cadherin cytoplasmic region

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

97149461..97184184 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)