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Zfp942 zinc finger protein 942 [ Mus musculus (house mouse) ]

Gene ID: 73233, updated on 17-Aug-2024

Summary

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Official Symbol
Zfp942provided by MGI
Official Full Name
zinc finger protein 942provided by MGI
Primary source
MGI:MGI:1920483
See related
Ensembl:ENSMUSG00000071267 AllianceGenome:MGI:1920483
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110048L19Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 3.3), placenta adult (RPKM 3.0) and 28 other tissues See more
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Genomic context

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See Zfp942 in Genome Data Viewer
Location:
17 A3.3; 17 11.4 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22145941..22181494, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21926960..21962503, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 995 Neighboring gene STARR-seq mESC enhancer starr_42020 Neighboring gene nuclease-sensitive element-binding protein 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E11628 Neighboring gene zinc finger prtoein 943 Neighboring gene 39S ribosomal protein L20, mitochondrial pseudogene Neighboring gene tropomyosin 4, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC107415

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC73233

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199048.1 → NP_001185977.1  uncharacterized protein LOC73233

    See identical proteins and their annotated locations for NP_001185977.1

    Status: VALIDATED

    Source sequence(s)
    AC154483, AK032425, AK136009, BE989651, CT009755
    Consensus CDS
    CCDS57052.1
    UniProtKB/TrEMBL
    B8JJA7, E9Q0I6
    Related
    ENSMUSP00000089494.6, ENSMUST00000091879.12
    Conserved Domains (5) summary
    COG5048
    Location:237 → 397
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:403 → 481
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 220
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    22145941..22181494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160802.1 → XP_036016695.1  uncharacterized protein LOC73233 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:199 → 359
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:365 → 443
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030250078.2 → XP_030105938.1  uncharacterized protein LOC73233 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:199 → 359
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:365 → 443
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_030250076.1 → XP_030105936.1  uncharacterized protein LOC73233 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:199 → 359
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:365 → 443
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_030250077.2 → XP_030105937.1  uncharacterized protein LOC73233 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:199 → 359
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:365 → 443
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_030250073.1 → XP_030105933.1  uncharacterized protein LOC73233 isoform X1

    UniProtKB/TrEMBL
    B8JJA7, E9Q0I6
    Conserved Domains (5) summary
    COG5048
    Location:237 → 397
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:403 → 481
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 220
    zf-H2C2_2; Zinc-finger double domain

  6. XM_030250074.1 → XP_030105934.1  uncharacterized protein LOC73233 isoform X1

    UniProtKB/TrEMBL
    B8JJA7, E9Q0I6
    Conserved Domains (5) summary
    COG5048
    Location:237 → 397
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:403 → 481
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 220
    zf-H2C2_2; Zinc-finger double domain

  7. XM_036160803.1 → XP_036016696.1  uncharacterized protein LOC73233 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:199 → 359
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:365 → 443
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. XM_030250075.2 → XP_030105935.1  uncharacterized protein LOC73233 isoform X1

    UniProtKB/TrEMBL
    B8JJA7, E9Q0I6
    Related
    ENSMUSP00000073907.8, ENSMUST00000074295.8
    Conserved Domains (5) summary
    COG5048
    Location:237 → 397
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:403 → 481
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 220
    zf-H2C2_2; Zinc-finger double domain

  9. XM_030250072.2 → XP_030105932.1  uncharacterized protein LOC73233 isoform X1

    UniProtKB/TrEMBL
    B8JJA7, E9Q0I6
    Conserved Domains (5) summary
    COG5048
    Location:237 → 397
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:403 → 481
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:325 → 345
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 52
    KRAB; KRAB box
    pfam13465
    Location:198 → 220
    zf-H2C2_2; Zinc-finger double domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003549.1: Suppressed sequence

    Description
    NR_003549.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

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