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CD74 CD74 molecule [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710820, updated on 17-Aug-2024

Summary

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Official Symbol
CD74provided by VGNC
Official Full Name
CD74 moleculeprovided by VGNC
Primary source
VGNC:VGNC:70779
See related
Ensembl:ENSMMUG00000009113
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CD74 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
9
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (147911733..147922838, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (148532565..148543667, complement)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene arylsulfatase family member I Neighboring gene treacle ribosome biogenesis factor 1 Neighboring gene ribosomal protein S14 Neighboring gene N-deacetylase and N-sulfotransferase 1 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables macrophage migration inhibitory factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antigen processing and presentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of DNA damage response, signal transduction by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type 2 immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein trimerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
HLA class II histocompatibility antigen gamma chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    147911733..147922838 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015141237.2 → XP_014996723.2  HLA class II histocompatibility antigen gamma chain isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q6A3, I0FWR3
    Related
    ENSMMUP00000043569.2, ENSMMUT00000068011.2
    Conserved Domains (2) summary
    pfam08831
    Location:134 → 202
    MHCassoc_trimer; Class II MHC-associated invariant chain trimerisation domain
    pfam09307
    Location:17 → 122
    MHC2-interact; CLIP, MHC2 interacting

  2. XM_015141236.2 → XP_014996722.2  HLA class II histocompatibility antigen gamma chain isoform X1

    UniProtKB/TrEMBL
    F7E9S4, G7MVM5, I0FWR4
    Related
    ENSMMUP00000011957.4, ENSMMUT00000012750.4
    Conserved Domains (3) summary
    cd00191
    Location:210 → 265
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    pfam08831
    Location:134 → 202
    MHCassoc_trimer; Class II MHC-associated invariant chain trimerisation domain
    pfam09307
    Location:17 → 126
    MHC2-interact; CLIP, MHC2 interacting
Nucleotide Protein
Heading Accession and Version

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