Conserved Protein Domain Family
MHC2-interact
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pfam09307: MHC2-interact (this model, PSSM-Id:312714 is obsolete and has been replaced by 462750)
CLIP, MHC2 interacting
Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.
Links
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Statistics
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PSSM-Id: 312714
Aligned: 9 rows
Threshold Bit Score: 99.8466
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P04441         1 MDDQRDLISN---HE---QLPILGNRPREPER-CSRGALYTGVSVLVALLLAGQATTAYFLYQQQGRLDKLTITSQNLQL 73  house mouse
XP_015205517   3 EEQHDALLKNegpPS---EETVVNVQTGQRSS-SNRGYKIAGFTLLACLLIAGQAVTVYFVMSQKGQITTLEQHTENLKK 78  spotted gar
XP_015463926   3 EPQEGPLLRT---PS---EQGSVGQPRGG--S-NKQALKVAGLTVLAAVLIAGQAFTAYMMYSQKDRLNSLESHSARLEE 73  Mexican tetra
XP_005988348   2 TDERQDLLRG---NEpslSESVVNINNEGR-S-TKRTILWTGLSIFVALLIAGQAVTVYFVMQQKGQITTLEQHSKNLEL 76  coelacanth
XP_007232273   3 DQQNSALLERa--PS---SDSF---TPPRSNA-NTKALKVAGLTLLACLLLAGQALTAYFVLGQRDHITALEQGQENLKV 73  Mexican tetra
NP_571665      4 DHQNESLIQRv--PS---AETILG-RGDARNS-NTKALKITGLTVLACLLLAGQALTAYMVWGQKQHINALTSGQEKLKA 76  zebrafish
AAT36345       2 AEEQRDLISS---DG---SSGVLPIGNSERSS-LGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKL 74  chicken
XP_016157118   2 AEEQRDLISD---RG----SGVLSVGDAQRSG-LRRKAAFSTLSILVALLIAGQAVTIYFVYQQSGQISKLTKTSQKMQL 73  collared flycat...
XP_004042867  17 MDDQRDLISN---NE---QLPMLGRRPGAPESkCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQL 90  western lowland...

P04441        74 ESLRMKLPKSAKPVsqmRMATPLLMRPMSMDNMLLGPV 111 house mouse
XP_015205517  79 QLNTRKPAPPSAPK---MLHMPMFNMPLLMDYSEDSKK 113 spotted gar
XP_015463926  74 --LGRRATVVRSPM---KMALPMNSLPLFLDESTTGDK 106 Mexican tetra
XP_005988348  77 TLRMKTFPKPKAP----RMMMPM-AIPLA--YSEDVDP 107 coelacanth
XP_007232273  74 QLMRRPSGGA---K---QMHVPMNSLPLMTSLSDDDVP 105 Mexican tetra
NP_571665     77 ELTRKMSAGA--Pk---AMSLPMNSMPLLKDYSDPTSD 109 zebrafish
AAT36345      75 ESLQRKMPIGTQPAnkmSMST--MNMPMAMKVLPLAPS 110 chicken
XP_016157118  74 DALQMKLPASAKPVnkmKMAK--ANTPLVMSALHPAPf 109 collared flycatcher
XP_004042867  91 ENLRMKLPKPPKPVskmRMATPLLMQALPMGALPQGPM 128 western lowland gorilla
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