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Ccdc90b coiled-coil domain containing 90B [ Mus musculus (house mouse) ]

Gene ID: 66365, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc90bprovided by MGI
Official Full Name
coiled-coil domain containing 90Bprovided by MGI
Primary source
MGI:MGI:1913615
See related
Ensembl:ENSMUSG00000030613 AllianceGenome:MGI:1913615
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310015N07Rik
Summary
Located in mitochondrion. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human CCDC90B (coiled-coil domain containing 90B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E11.5 (RPKM 12.7), CNS E14 (RPKM 12.1) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc90b in Genome Data Viewer
Location:
7 E1; 7 51.51 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (92210350..92231502)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (92561149..92582294)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 2 Neighboring gene predicted gene, 53382 Neighboring gene STARR-seq mESC enhancer starr_19525 Neighboring gene predicted gene, 31491 Neighboring gene STARR-positive B cell enhancer ABC_E6571 Neighboring gene STARR-positive B cell enhancer ABC_E291 Neighboring gene STARR-seq mESC enhancer starr_19528 Neighboring gene ankyrin repeat domain 42 Neighboring gene predicted gene, 26944 Neighboring gene pantothenate kinase 1 pseudogene Neighboring gene PCF11 cleavage and polyadenylation factor subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC144297

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 90B, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162918.1 → NP_001156390.1  coiled-coil domain-containing protein 90B, mitochondrial isoform 2

    See identical proteins and their annotated locations for NP_001156390.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter compared to isoform 1.
    Source sequence(s)
    BB617939, BC034878
    Consensus CDS
    CCDS52309.1
    UniProtKB/Swiss-Prot
    Q8C3X2
    Related
    ENSMUSP00000082090.5, ENSMUST00000085017.5
    Conserved Domains (1) summary
    pfam07798
    Location:61 → 218
    DUF1640; Protein of unknown function (DUF1640)

  2. NM_025515.3 → NP_079791.2  coiled-coil domain-containing protein 90B, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_079791.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AI643175, AK084673, BB617939, BC034878
    Consensus CDS
    CCDS21449.1
    UniProtKB/Swiss-Prot
    Q8C3X2, Q8JZY3, Q9D7C1
    Related
    ENSMUSP00000032842.7, ENSMUST00000032842.13
    Conserved Domains (1) summary
    pfam07798
    Location:61 → 252
    DUF1640; Protein of unknown function (DUF1640)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    92210350..92231502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153349.1 → XP_036009242.1  coiled-coil domain-containing protein 90B, mitochondrial isoform X1

    Conserved Domains (1) summary
    pfam07798
    Location:1 → 151
    DUF1640; Protein of unknown function (DUF1640)

  2. XM_036153350.1 → XP_036009243.1  coiled-coil domain-containing protein 90B, mitochondrial isoform X1

    Conserved Domains (1) summary
    pfam07798
    Location:1 → 151
    DUF1640; Protein of unknown function (DUF1640)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C3X2.1 GenPept UniProtKB/Swiss-Prot:Q8C3X2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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