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ndrg4.S NDRG family member 4 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447761, updated on 4-Nov-2024

Summary

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Official Symbol
ndrg4.S
Official Full Name
NDRG family member 4 S homeolog
Primary source
Xenbase:XB-GENE-941133
Locus tag
XELAEV_18024991mg
See related
EnsemblRapid:ENSXLAG00005018175 AllianceGenome:Xenbase:XB-GENE-941133
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
smap-8; ndrg4-a; ndrg4-b
Summary
Predicted to act upstream of or within positive regulation of ERK1 and ERK2 cascade and signal transduction. Predicted to be located in cytosol. Orthologous to human NDRG4 (NDRG family member 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ndrg4.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (55370652..55461418, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (49262457..49325662, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel beta 1 S homeolog Neighboring gene zinc finger protein 319 S homeolog Neighboring gene casein kinase 2 alpha 2 S homeolog Neighboring gene matrix metallopeptidase 15 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84035

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein NDRG4-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094431.1 → NP_001087900.1  protein NDRG4-A

    See identical proteins and their annotated locations for NP_001087900.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082448
    UniProtKB/Swiss-Prot
    Q5XGS5, Q640Z1
    UniProtKB/TrEMBL
    A0A974D129
    Related
    ENSXLAP00005053681.1, ENSXLAT00005054854.1
    Conserved Domains (2) summary
    TIGR02427
    Location:68 → 335
    protocat_pcaD; 3-oxoadipate enol-lactonase
    pfam03096
    Location:59 → 341
    Ndr; Ndr family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    55370652..55461418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041591371.1 → XP_041447305.1  protein NDRG4-A isoform X1

    UniProtKB/TrEMBL
    A0A8J1N2A9
    Conserved Domains (1) summary
    COG0596
    Location:116 → 339
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

  2. XM_041591373.1 → XP_041447307.1  protein NDRG4-A isoform X3

    UniProtKB/TrEMBL
    A0A8J1MZV0
    Conserved Domains (1) summary
    COG0596
    Location:116 → 339
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

  3. XM_018259665.2 → XP_018115154.1  protein NDRG4-A isoform X4

    UniProtKB/Swiss-Prot
    Q640Z1
    Related
    ENSXLAP00005053693.1, ENSXLAT00005054866.1

  4. XM_041591374.1 → XP_041447308.1  protein NDRG4-A isoform X7

    UniProtKB/TrEMBL
    A0A8J1N1J8
    Related
    ENSXLAP00005053673.1, ENSXLAT00005054846.1
    Conserved Domains (1) summary
    COG0596
    Location:113 → 336
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

  5. XM_041591372.1 → XP_041447306.1  protein NDRG4-A isoform X2

    UniProtKB/TrEMBL
    A0A8J1N0R6
    Conserved Domains (1) summary
    COG0596
    Location:115 → 338
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

  6. XM_018259666.2 → XP_018115155.1  protein NDRG4-A isoform X5

    UniProtKB/TrEMBL
    A0A8J0V001

  7. XM_018259664.2 → XP_018115153.1  protein NDRG4-A isoform X6

    UniProtKB/TrEMBL
    A0A8J0V935
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q640Z1.1 GenPept UniProtKB/Swiss-Prot:Q640Z1

Gene LinkOut

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