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arhgap1.S Rho GTPase activating protein 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446344, updated on 4-Nov-2024

Summary

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Official Symbol
arhgap1.S
Official Full Name
Rho GTPase activating protein 1 S homeolog
Primary source
Xenbase:XB-GENE-6251491
Locus tag
XELAEV_18024483mg
See related
EnsemblRapid:ENSXLAG00005020484 AllianceGenome:Xenbase:XB-GENE-6251491
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rhogap; arhgap1; rhogap1; cdc42gap; arhgap1-a; arhgap1-b; p50rhogap; rhogap68f
Summary
Predicted to enable GTPase activator activity. Predicted to act upstream of or within negative regulation of endocytic recycling and small GTPase-mediated signal transduction. Predicted to be located in cytoplasm and membrane. Orthologous to human ARHGAP1 (Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See arhgap1.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (14751933..14778010, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (14156185..14182190, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene autophagy related 13 S homeolog Neighboring gene SPRY domain-containing SOCS box protein 3 Neighboring gene zinc finger protein 408 S homeolog Neighboring gene coagulation factor II, thrombin S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC81361

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of endocytic recycling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rho GTPase activating protein 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093040.1 → NP_001086509.1  Rho GTPase activating protein 1 S homeolog

    See identical proteins and their annotated locations for NP_001086509.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076733
    UniProtKB/TrEMBL
    A0A974HMM9, Q6DFK3
    Related
    ENSXLAP00005059987.1, ENSXLAT00005061436.1
    Conserved Domains (3) summary
    cd04404
    Location:238 → 430
    RhoGAP-p50rhoGAP; RhoGAP-p50rhoGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p50RhoGAP-like proteins; p50RhoGAP, also known as RhoGAP-1, contains a C-terminal RhoGAP domain and an N-terminal Sec14 domain which binds phosphatidylinositol ...
    pfam13716
    Location:83 → 207
    CRAL_TRIO_2; Divergent CRAL/TRIO domain
    cl00234
    Location:62 → 102
    Pep_deformylase; Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II) ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    14751933..14778010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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