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KDM2A lysine (K)-specific demethylase 2A [ Gallus gallus (chicken) ]

Gene ID: 425999, updated on 17-Aug-2024

Summary

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Official Symbol
KDM2Aprovided by CGNC
Official Full Name
lysine (K)-specific demethylase 2Aprovided by CGNC
Primary source
CGNC:10022
See related
Ensembl:ENSGALG00010023166
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
FBXL11
Orthologs
human mouse all
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Genomic context

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See KDM2A in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (87266..121423)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (85603..119687)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene proto-oncogene Mas-like Neighboring gene proto-oncogene Mas-like Neighboring gene ras homolog family member D Neighboring gene uncharacterized LOC121110883 Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene ankyrin repeat domain 13D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lysine-specific demethylase 2A
Names
F-box and leucine-rich repeat protein 11
XP_015128110.1
XP_015128112.1
XP_040528401.1
XP_040528402.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    87266..121423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015272624.4 → XP_015128110.1  lysine-specific demethylase 2A isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U6R1, A0A8V0ZUS4
    Related
    ENSGALP00010034212.1, ENSGALT00010056468.1
    Conserved Domains (9) summary
    cd09293
    Location:974 → 1178
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:189 → 260
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:973 → 997
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15643
    Location:662 → 718
    PHD_KDM2A; PHD finger found in Lysine-specific demethylase 2A (KDM2A)
    pfam02008
    Location:619 → 652
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:939 → 977
    F-box-like
    pfam17811
    Location:341 → 376
    JHD; Jumonji helical domain
    cd21784
    Location:494 → 561
    CTD_KDM2A; C-terminal domain found in Lysine-specific demethylase 2A
    cl40423
    Location:236 → 336
    cupin_RmlC-like; RmlC-like cupin superfamily

  2. XM_015272626.3 → XP_015128112.1  lysine-specific demethylase 2A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZUS4
    Conserved Domains (9) summary
    cd09293
    Location:937 → 1141
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:152 → 223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:936 → 960
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15643
    Location:625 → 681
    PHD_KDM2A; PHD finger found in Lysine-specific demethylase 2A (KDM2A)
    pfam02008
    Location:582 → 615
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:902 → 940
    F-box-like
    pfam17811
    Location:304 → 339
    JHD; Jumonji helical domain
    cd21784
    Location:457 → 524
    CTD_KDM2A; C-terminal domain found in Lysine-specific demethylase 2A
    cl40423
    Location:199 → 299
    cupin_RmlC-like; RmlC-like cupin superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    85603..119687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040672467.2 → XP_040528401.1  lysine-specific demethylase 2A isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U6R1, A0A8V0ZUS4
    Conserved Domains (9) summary
    cd09293
    Location:974 → 1178
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:189 → 260
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:973 → 997
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15643
    Location:662 → 718
    PHD_KDM2A; PHD finger found in Lysine-specific demethylase 2A (KDM2A)
    pfam02008
    Location:619 → 652
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:939 → 977
    F-box-like
    pfam17811
    Location:341 → 376
    JHD; Jumonji helical domain
    cd21784
    Location:494 → 561
    CTD_KDM2A; C-terminal domain found in Lysine-specific demethylase 2A
    cl40423
    Location:236 → 336
    cupin_RmlC-like; RmlC-like cupin superfamily

  2. XM_040672468.2 → XP_040528402.1  lysine-specific demethylase 2A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZUS4
    Conserved Domains (9) summary
    cd09293
    Location:937 → 1141
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:152 → 223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:936 → 960
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15643
    Location:625 → 681
    PHD_KDM2A; PHD finger found in Lysine-specific demethylase 2A (KDM2A)
    pfam02008
    Location:582 → 615
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:902 → 940
    F-box-like
    pfam17811
    Location:304 → 339
    JHD; Jumonji helical domain
    cd21784
    Location:457 → 524
    CTD_KDM2A; C-terminal domain found in Lysine-specific demethylase 2A
    cl40423
    Location:199 → 299
    cupin_RmlC-like; RmlC-like cupin superfamily
Nucleotide Protein Strain
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