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MTIF2 mitochondrial translational initiation factor 2 [ Gallus gallus (chicken) ]

Gene ID: 421213, updated on 17-Aug-2024

Summary

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Symbol
MTIF2provided by CGNC
Full Name
mitochondrial translational initiation factor 2provided by CGNC
Primary source
CGNC:6152
See related
Ensembl:ENSGALG00010016778
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (138926..149874, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (104644..115590, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110462 Neighboring gene ribosomal protein S27a Neighboring gene prolyl-tRNA synthetase associated domain containing 1, pseudogene Neighboring gene coiled-coil domain containing 88A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translation initiation factor IF-2, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199424.2 → NP_001186353.1  translation initiation factor IF-2, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000059
    UniProtKB/TrEMBL
    A0A8V0YXW5
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 719
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:509 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 710
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 447
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    138926..149874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040696979.2 → XP_040552913.1  translation initiation factor IF-2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXW5
    Conserved Domains (1) summary
    cl30717
    Location:90 → 676
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]

  2. XM_040696980.2 → XP_040552914.1  translation initiation factor IF-2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8V0YR29, A0A8V0YXW5
    Conserved Domains (1) summary
    cl30717
    Location:90 → 675
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]

  3. XM_015283309.4 → XP_015138795.1  translation initiation factor IF-2, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXW5
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 719
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:509 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 710
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 447
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  4. XM_015283310.4 → XP_015138796.1  translation initiation factor IF-2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXW5
    Conserved Domains (1) summary
    cl30717
    Location:90 → 676
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]

  5. XM_025148625.3 → XP_025004393.1  translation initiation factor IF-2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8V0YR29, A0A8V0YXW5
    Related
    ENSGALP00010023478.1, ENSGALT00010040459.1
    Conserved Domains (1) summary
    cl30717
    Location:90 → 675
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]

  6. XM_046938668.1 → XP_046794624.1  translation initiation factor IF-2, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8V0YXW5

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    104644..115590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913506.1 → XP_046769462.1  translation initiation factor IF-2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXW5

  2. XM_046913508.1 → XP_046769464.1  translation initiation factor IF-2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8V0YXW5

  3. XM_046913504.1 → XP_046769460.1  translation initiation factor IF-2, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXW5

  4. XM_046913505.1 → XP_046769461.1  translation initiation factor IF-2, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXW5

  5. XM_046913507.1 → XP_046769463.1  translation initiation factor IF-2, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8V0YXW5
Nucleotide Protein Strain
Heading Accession and Version

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