arhgap35.L Rho GTPase activating protein 35 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: arhgap35.L
Official Full Name: Rho GTPase activating protein 35 L homeolog
Primary source: Xenbase:XB-GENE-999480
Locus tag: XELAEV_18039043mg
See related: EnsemblRapid:ENSXLAG00005030362
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: grf-1; grlf1; p190a; p190-a; arhgap35; p190rhogap; p190arhogap
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Genomic context

Location:: chromosome: 8L

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (62166734..62199808, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (48979133..49012439, complement)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables lipid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Rho protein signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of axonogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell size	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: rho GTPase-activating protein 35

Names: Rho GAP p190A; glucocorticoid receptor DNA binding factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091205.1 → NP_001084674.1 rho GTPase-activating protein 35

See identical proteins and their annotated locations for NP_001084674.1

Status: PROVISIONAL

Source sequence(s)

BC068777

UniProtKB/Swiss-Prot

Q6NU25

Conserved Domains (5) summary

smart00441
Location:429 → 470

FF; Contains two conserved F residues

cd00882
Location:29 → 245

Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)

cd04373
Location:1241 → 1425

RhoGAP_p190; RhoGAP_p190: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and ...

pfam16512
Location:261 → 340

RhoGAP-FF1; p190-A and -B Rho GAPs FF domain

cl27030
Location:157 → 250

Ras; Ras family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

62166734..62199808 complement

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GenBank, FASTA, Sequence Viewer (Graphics)