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Tim17a2 Tim17a2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40632, updated on 2-Nov-2024

Summary

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Official Symbol
Tim17a2provided by FlyBase
Official Full Name
Tim17a2provided by FlyBase
Primary source
FLYBASE:FBgn0037307
Locus tag
Dmel_CG14666
See related
AllianceGenome:FB:FBgn0037307
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH03914; CG14666; Dmel\CG14666
Summary
Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Orthologous to human TIMM17A (translocase of inner mitochondrial membrane 17A) and TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See Tim17a2 in Genome Data Viewer
Location:
82F7-82F8; 3-47.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5258336..5262692, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1084058..1088414, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Enolase-phosphatase Neighboring gene HIF prolyl hydroxylase Neighboring gene long non-coding RNA:CR45793 Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of the Tim17 protein family. Žárský V, et al. Biol Direct, 2016 Oct 19. PMID 27760563, Free PMC Article
  2. Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. Langille MG, et al. Genomics, 2007 Sep. PMID 17628393
  3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
  4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c5261102-5259374 mobile_element_type = transposon:S{}1217

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tim17a2
Names
CG14666-PA
Tim17a2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5258336..5262692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141267.3 → NP_649524.1  Tim17a2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649524.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VN97
    Related
    FBpp0078462
    Conserved Domains (1) summary
    cl02381
    Location:2 → 129
    Tim17; Tim17/Tim22/Tim23/Pmp24 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYA9 Q8SYA9
Q9VN97.1 Q9VN97

Gene LinkOut

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