EIF5B eukaryotic translation initiation factor 5B [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: EIF5Bprovided by CGNC
Official Full Name: eukaryotic translation initiation factor 5Bprovided by CGNC
Primary source: CGNC:12572
See related: Ensembl:ENSGALG00010015870
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: CIF2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (132664089..132694769)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (132622238..132652924)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

involved in protein synthesis
Title: Expression of translation initiation factor IF2 is regulated during osteoblast differentiation.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: eukaryotic translation initiation factor 5B

Names: initiation of translation factor 2

NP_001033585.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001038496.2 → NP_001033585.1 eukaryotic translation initiation factor 5B

Status: VALIDATED

Source sequence(s)

JAENSK010000025

UniProtKB/TrEMBL

A0A8V0Z0C8, E1BVP1

Related

ENSGALP00010022081.1, ENSGALT00010038252.1

Conserved Domains (5) summary

cd01887
Location:632 → 845

IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family

PRK04004
Location:627 → 1202

PRK04004; translation initiation factor IF-2; Validated

pfam11987
Location:966 → 1067

IF-2; Translation-initiation factor 2

cd03703
Location:855 → 965

aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5

cd16266
Location:1092 → 1186

IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5