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ubqln4 ubiquilin 4 [ Danio rerio (zebrafish) ]

Gene ID: 334337, updated on 12-Sep-2024

Summary

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Official Symbol
ubqln4provided by ZNC
Official Full Name
ubiquilin 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6269
See related
Ensembl:ENSDARG00000052975 AllianceGenome:ZFIN:ZDB-GENE-030131-6269
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ubin; zgc:66188; wu:fb48e11; wu:fb54b10; wu:fi41e06; zgc:113928
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. Is expressed in muscle and trunk. Orthologous to human UBQLN4 (ubiquilin 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See ubqln4 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (46666175..46681170)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (46699459..46714454)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 176l.2 Neighboring gene transmembrane protein 176l.4 Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neighboring gene RAB25, member RAS oncogene family b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Mechanism of toxic effects of Nano-ZnO on cell cycle of zebrafish (Danio rerio). Hou J, et al. Chemosphere, 2019 Aug. PMID 31078877
  2. ALS-associated genes display CNS expression in the developing zebrafish. Laboissonniere LA, et al. Gene Expr Patterns, 2018 Dec. PMID 30165106
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC113928

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquilin-4
Names
ataxin-1 ubiquitin-like interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213356.2 → NP_998521.2  ubiquilin-4

    See identical proteins and their annotated locations for NP_998521.2

    Status: PROVISIONAL

    Source sequence(s)
    BC098879
    UniProtKB/TrEMBL
    Q4G000
    Related
    ENSDARP00000069405.3, ENSDART00000074919.5
    Conserved Domains (4) summary
    smart00727
    Location:186 → 223
    STI1; Heat shock chaperonin-binding motif
    cd01808
    Location:26 → 96
    hPLIC_N; Ubiquitin-like domain of hPLIC-1 and hPLIC2
    smart00213
    Location:26 → 96
    UBQ; Ubiquitin homologues
    cd14399
    Location:556 → 595
    UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    46666175..46681170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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