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CG31915 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 319025, updated on 10-May-2024

Summary

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Official Symbol
CG31915provided by FlyBase
Primary source
FLYBASE:FBgn0051915
Locus tag
Dmel_CG31915
See related
AllianceGenome:FB:FBgn0051915
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6922; Dmel\CG31915
Summary
Predicted to enable procollagen galactosyltransferase activity. Predicted to be involved in positive regulation of collagen fibril organization. Predicted to be located in endoplasmic reticulum lumen. Is expressed in adult head. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Orthologous to several human genes including COLGALT1 (collagen beta(1-O)galactosyltransferase 1) and COLGALT2 (collagen beta(1-O)galactosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG31915 in Genome Data Viewer
Location:
25E5-25E5; 2-17 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5528123..5530682)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5528123..5530682)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44793 Neighboring gene Elongator complex protein 4 Neighboring gene Chromosome associated protein D3 Neighboring gene Cytochrome c oxidase copper chaperone COX11 Neighboring gene Coenzyme Q6 Neighboring gene tombola Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions. Sakaidani Y, et al. Nat Commun, 2011 Dec 13. PMID 22158438
  2. Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early. Jiang J, et al. Development, 2007 Apr. PMID 17360778, Free PMC Article
  3. Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Rehwinkel J, et al. Nat Struct Mol Biol, 2004 Jun. PMID 15133499
  4. A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Baumbach J, et al. Cell Metab, 2014 Feb 4. PMID 24506874
  5. Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Engström PG, et al. Genome Res, 2007 Dec. PMID 17989259, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables procollagen galactosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables procollagen galactosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of collagen fibril organization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum lumen ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31915-PA
NP_723087.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5528123..5530682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164645.3 → NP_723087.1  uncharacterized protein Dmel_CG31915 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723087.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9UNF8, Q8IPK4
    Related
    FBpp0078732
    Conserved Domains (2) summary
    cd06532
    Location:334 → 515
    Glyco_transf_25; Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of ...
    cl11394
    Location:32 → 146
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IPK4.1 Q8IPK4

Gene LinkOut

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