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CG3823 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31573, updated on 2-Nov-2024

Summary

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Official Symbol
CG3823provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029863
Locus tag
Dmel_CG3823
See related
AllianceGenome:FB:FBgn0029863
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3823
Summary
Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CG3823 in Genome Data Viewer
Location:
5E7-5E8; 1-16 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6303975..6306745)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6198008..6200778)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Changes in Drosophila melanogaster midgut proteins in response to dietary Bowman-Birk inhibitor. Li HM, et al. Insect Mol Biol, 2007 Oct. PMID 17725801
  2. Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation. Liu J, et al. Hereditas, 2022 Oct 21. PMID 36271387, Free PMC Article
  3. Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Beckstead RB, et al. Insect Biochem Mol Biol, 2007 Jun. PMID 17517334, Free PMC Article
  4. RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models. Zhang X, et al. Heliyon, 2023 May. PMID 37251843, Free PMC Article
  5. Two subunits specific to the PBAP chromatin remodeling complex have distinct and redundant functions during drosophila development. Carrera I, et al. Mol Cell Biol, 2008 Sep. PMID 18573871, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in intermembrane lipid transfer ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in late endosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3823-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    6303975..6306745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132085.2 → NP_572313.1  uncharacterized protein Dmel_CG3823 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572313.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W408
    Related
    FBpp0070865
    Conserved Domains (1) summary
    cd00170
    Location:90 → 239
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W408 Q9W408

Gene LinkOut

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