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Ccdc91 coiled-coil domain containing 91 [ Rattus norvegicus (Norway rat) ]

Gene ID: 312863, updated on 17-Aug-2024

Summary

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Symbol
Ccdc91provided by RGD
Full Name
coiled-coil domain containing 91provided by RGD
Primary source
RGD:1359502
See related
EnsemblRapid:ENSRNOG00000001847 AllianceGenome:RGD:1359502
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in Golgi to lysosome transport. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in trans-Golgi network. Orthologous to human CCDC91 (coiled-coil domain containing 91). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 719.0), Muscle (RPKM 312.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc91 in Genome Data Viewer
Location:
4q44
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (182132931..182304948)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (180402327..180574364)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (181873465..182043593)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350879 Neighboring gene parathyroid hormone-like hormone Neighboring gene uncharacterized LOC134486874 Neighboring gene uncharacterized LOC108350795 Neighboring gene fatty acyl CoA reductase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. Mardones GA, et al. Mol Biol Cell, 2007 Sep. PMID 17596511, Free PMC Article
  2. Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. Lui WW, et al. Mol Biol Cell, 2003 Jun. PMID 12808037, Free PMC Article
  3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi to lysosome transport ISO
Inferred from Sequence Orthology
more info
  
involved_in Golgi to lysosome transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in Golgi vesicle transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
  
located_in trans-Golgi network ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 91
Names
GGA-binding partner
coiled-coil domain-containing protein 91-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014061.1 → NP_001014083.1  coiled-coil domain-containing protein 91

    See identical proteins and their annotated locations for NP_001014083.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079135
    UniProtKB/Swiss-Prot
    Q6AY97
    UniProtKB/TrEMBL
    A0A8I6G845
    Related
    ENSRNOP00000002527.6, ENSRNOT00000002527.8
    Conserved Domains (1) summary
    pfam17380
    Location:130 → 442
    DUF5401; Family of unknown function (DUF5401)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    182132931..182304948
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286194.1 → XP_063142264.1  coiled-coil domain-containing protein 91 isoform X5

    UniProtKB/TrEMBL
    A0A8I6G845

  2. XM_006237685.5 → XP_006237747.1  coiled-coil domain-containing protein 91 isoform X3

    UniProtKB/TrEMBL
    A0A8I6AS44, A0A8I6G845
    Related
    ENSRNOP00000097935.1, ENSRNOT00000099526.2
    Conserved Domains (1) summary
    PTZ00121
    Location:143 → 387
    PTZ00121; MAEBL; Provisional

  3. XM_063286192.1 → XP_063142262.1  coiled-coil domain-containing protein 91 isoform X1

    UniProtKB/Swiss-Prot
    Q6AY97
    UniProtKB/TrEMBL
    A0A8I6G845

  4. XM_063286190.1 → XP_063142260.1  coiled-coil domain-containing protein 91 isoform X1

    UniProtKB/Swiss-Prot
    Q6AY97
    UniProtKB/TrEMBL
    A0A8I6G845

  5. XM_039107721.2 → XP_038963649.1  coiled-coil domain-containing protein 91 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G845
    Conserved Domains (1) summary
    pfam17380
    Location:110 → 422
    DUF5401; Family of unknown function (DUF5401)

  6. XM_008763456.4 → XP_008761678.1  coiled-coil domain-containing protein 91 isoform X1

    See identical proteins and their annotated locations for XP_008761678.1

    UniProtKB/Swiss-Prot
    Q6AY97
    UniProtKB/TrEMBL
    A0A8I6G845
    Conserved Domains (1) summary
    pfam17380
    Location:130 → 442
    DUF5401; Family of unknown function (DUF5401)

  7. XM_063286193.1 → XP_063142263.1  coiled-coil domain-containing protein 91 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G845

  8. XM_006237686.5 → XP_006237748.1  coiled-coil domain-containing protein 91 isoform X4

    UniProtKB/TrEMBL
    A0A8I6A3R2, A0A8I6G845
    Related
    ENSRNOP00000081556.2, ENSRNOT00000108480.2
    Conserved Domains (1) summary
    pfam07851
    Location:149 → 256
    TMPIT; TMPIT-like protein

  9. XM_006237687.5 → XP_006237749.1  coiled-coil domain-containing protein 91 isoform X6

    UniProtKB/TrEMBL
    A0A8I6G845
    Conserved Domains (1) summary
    PTZ00121
    Location:113 → 340
    PTZ00121; MAEBL; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AY97.1 GenPept UniProtKB/Swiss-Prot:Q6AY97

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