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mrpl24 mitochondrial ribosomal protein L24 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295224, updated on 17-Aug-2024

Summary

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Symbol
mrpl24provided by RGD
Full Name
mitochondrial ribosomal protein L24provided by RGD
Primary source
RGD:1359289
See related
EnsemblRapid:ENSRNOG00000022234 AllianceGenome:RGD:1359289
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPL24 (mitochondrial ribosomal protein L24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 178.9), Muscle (RPKM 168.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See mrpl24 in Genome Data Viewer
Location:
2q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175680872..175687107)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173383062..173389249)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187288460..187294676)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene proline rich mitotic checkpoint control factor Neighboring gene heparin binding growth factor Neighboring gene methyltransferase like 25B Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene cellular retinoic acid binding protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mammalian mitochondrial ribosomal proteins (4). Amino acid sequencing, characterization, and identification of corresponding gene sequences. O'Brien TW, et al. J Biol Chem, 2000 Jun 16. PMID 10751423
  2. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC94307

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL24m
Names
39S ribosomal protein L24, mitochondrial
L24mt
MRP-L24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007637.1 → NP_001007638.1  large ribosomal subunit protein uL24m precursor

    See identical proteins and their annotated locations for NP_001007638.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082018
    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631
    Conserved Domains (1) summary
    cl00354
    Location:59 → 154
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    175680872..175687107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006232604.5 → XP_006232666.1  large ribosomal subunit protein uL24m isoform X1

    See identical proteins and their annotated locations for XP_006232666.1

    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631
    Related
    ENSRNOP00000034042.4, ENSRNOT00000035271.5
    Conserved Domains (1) summary
    cl00354
    Location:59 → 154
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  2. XM_006232607.5 → XP_006232669.1  large ribosomal subunit protein uL24m isoform X1

    See identical proteins and their annotated locations for XP_006232669.1

    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631
    Conserved Domains (1) summary
    cl00354
    Location:59 → 154
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  3. XM_006232605.5 → XP_006232667.1  large ribosomal subunit protein uL24m isoform X1

    See identical proteins and their annotated locations for XP_006232667.1

    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631
    Conserved Domains (1) summary
    cl00354
    Location:59 → 154
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  4. XM_063281599.1 → XP_063137669.1  large ribosomal subunit protein uL24m isoform X1

    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631

  5. XM_006232608.5 → XP_006232670.1  large ribosomal subunit protein uL24m isoform X1

    See identical proteins and their annotated locations for XP_006232670.1

    UniProtKB/Swiss-Prot
    Q66H47
    UniProtKB/TrEMBL
    A6J631
    Conserved Domains (1) summary
    cl00354
    Location:59 → 154
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66H47.1 GenPept UniProtKB/Swiss-Prot:Q66H47

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